SKIN REACTION AT SITE OF INTRATHECAL METHOTREXATE
Journal Title: World Journal of Pharmaceutical Research - Year 2019, Vol 8, Issue 9
Abstract
Complication of intrathecal methotrexate is an issue that is well documented, but development of a dermatological complication like skin burn following administration of intrathecal methotrexate is an extremely rare entity. A 24-year-old female with the diagnosis of acute lymphocytic leukemia (ALL) was put on a treatment regimen, including intrathecal methotrexate. After 2 days following intrathecal methotrexate administration, patient developed burn like skin lesion at site of administration. There was no history of trauma. Intrathecal skin burn may be a very rare, but serious, complication of intrathecal methotrexate administration.
Authors and Affiliations
Dr. Ahmed Mjali
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