Solitary Oral Mucosal Neuromas: A Rare Case Report

Journal Title: Scholars Journal of Medical Case Reports - Year 2014, Vol 2, Issue 4

Abstract

Abstract: Mucosal neuromas are a form of neurogenic tumour that arises in the oral cavity as a component of multiple endocrine neoplasia type 2b (MEN 2b). The syndrome is characterized with other features like tumors of the endocrine glands and skeletal abnormalities. Mutation at codon 918 of the RET protooncogene is a consistent feature among people affected with MEN 2. There are few reports describing pure mucosal neuromas without characteristics of MEN 2B . Analysis of the RET protooncogene among these cases have demonstrated no point mutation in the MEN 2B region (M918T). Hence, it is a subject of debate whether such anomalies should be considered as a different entity or a milder form of the MEN 2B syndrome. We report a case of 25 year old male patient who presented with multiple neuromas over the labial mucosa, tongue and floor of the mouth with no other features of MEN 2B. Keywords: Mucosal Neuromas, Neurogenic tumor, Multiple Endocrine Neoplasia type 2B, RET protooncogene, Point mutations

Authors and Affiliations

Umashree N, Hemant Shakya, Mona shakya

Keywords

Related Articles

Relation of Obesity and Hypothyroidism: A Case Report

Obesity, as a health problem is characterized by increased adipose tissue. There is several genetical and environmental reasons for increased adipose tissue. However, various pathological processes seem coincident with o...

Quinine Induced Headache and Visual Disturbances: A Case Report

Quinine is the chief alkaloid of cinchona, the powdered bark of the South American cinchona tree.Resistance to quinine is uncommon but increasing. It acts primarily against asexual erythrocytic forms and associated with...

Erdheim-Chester Disease: MR and PET/CT Findings of a Rare Case with Extensive Bone Lesions and Review of the Literature

Erdheim-Chester Disease is a rare, non-Langerhans cell histiocytosis firstly described in 1930. It may effect all age groups, but more commonly in males between the 5th and 7th decades of life. The etiopathogenesis is no...

Systemic lupus erythematosus in paediatric age group: A rare clinical presentation

Systemic lupus erythematosus (SLE) is an autoimmune disease in which organs and cells undergo damage mediated by tissue-binding autoantibodies and immune complexes. Ninety percent of patients are women of child-bearing a...

An Atypical Localization of Secondary Tuberculosis: Buccal Mucosa

Primary and secondary tuberculosis (TB) of the oral cavity is relatively rare and has largely become a forgotten diagnosis in oral lesions. This case report describes a refractory painless oral ulcer as secondary lesion...

Download PDF file
  • EP ID EP375498
  • DOI -
  • Views 89
  • Downloads 0

How To Cite

Umashree N, Hemant Shakya, Mona shakya (2014). Solitary Oral Mucosal Neuromas: A Rare Case Report. Scholars Journal of Medical Case Reports, 2(4), 239-241. https://europub.co.uk/articles/-A-375498