SOLUBILITY IMPROVEMENT USING SOLID DISPERSION; STRATEGY, MECHANISM AND CHARACTERIZATION: RESPONSIVENESS AND PROSPECT WAY OUTS
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2011, Vol 2, Issue 1
Abstract
New chemicals entities, being synthesized by various techniques, successfully present superior pharmacological activities. However 35-40 % of these new chemicals entities suffer from poor aqueous solubility. The current review extensively highlights various approaches used to enhance solubility, mechanisms responsible for improvement of solubility and characterization. This review also presents attentiveness amongst investigators working on this area and proposes assured promising way outs to improve solubility to obtain stable and effective final products.
Authors and Affiliations
Dinesh Sharma , Vipin Gupta , Suresh Purohit
Keywords
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