Solventless coating for Tablets: An alternative to conventional coating technique
Journal Title: Indian Journal of Pharmaceutical and Biological Research - Year 2014, Vol 2, Issue 2
Abstract
There are many ways to coat tablets. Coatings are a very important part in the formulation of pharmaceutical dosage form to achieve excellent formulation quality (e.g., color, texture, mouth feel, and taste masking), physical and chemical protection for the drugs in the dosage forms, and modification of drug release characteristics. Most film coatings are applied as aqueous or organic-based polymer solutions. Such film coating brings their own disadvantages. Solventless coatings are alternative technique of coating. Solventless coating technologies can overcome many of the disadvantages associated with the use of solvents (e.g., solvent exposure, solvent disposal, and residual solvent in product) in pharmaceutical coating. Solventless processing reduces the overall cost by eliminating the tedious and expensive processes of solvent disposal/treatment. In addition, it can significantly reduce the processing time due to reduction of step of drying/evaporation. These environment-friendly processes are performed without any heat in most cases (except hot-melt coating) and thus can provide an alternative technology to coat temperature-sensitive drugs. This review includes various solventless coating methods like magnetic assisted impaction coating , hotmelt coating, supercritical fluid spray coating, electrostatic coating, dry powder coating, and photocurable coating that can be used to coat the pharmaceutical dosage forms.
Authors and Affiliations
Manish Jaimini| Department of pharmaceutics, Jaipur College of Pharmacy, ISI-15, RIICO, Sitapura Institutional Area, Sitapura, Jaipur (Raj.), India, Arpit Jain| Department of pharmaceutics, Jaipur College of Pharmacy, ISI-15, RIICO, Sitapura Institutional Area, Sitapura, Jaipur (Raj.), India, Sanjay K. Sharma| Department of pharmaceutics, Jaipur College of Pharmacy, ISI-15, RIICO, Sitapura Institutional Area, Sitapura, Jaipur (Raj.), India, Shailender Mohan| Department of pharmaceutics, Jaipur College of Pharmacy, ISI-15, RIICO, Sitapura Institutional Area, Sitapura, Jaipur (Raj.), India
Keywords
Related Articles
- EP ID EP14156
- DOI -
- Views 385
- Downloads 22
Antibacterial and antifungal evaluation of some chalcogen bearing ligands, their transition and nontransition metal complexes
Eight chalcogen bearing compounds, 3-(4-fluorophenyl telluro) propylamine (1), 3-(phenyl telluro)propylammonium acetate salt (2), 3-(phenyl telluro)propylacetamide (3) and α-(phenylseleno) acetic acid (4) (1-4 are lig...
Dendrimer: a novel approach for drug delivery systems
Dendrimers are hyper-branched macromolecules having tree like structure, consisting of a core molecule and alternating layers of monomers. So they can be synthesized by divergent and convergent growth methods. During syn...
Neuroprotective Effect of Cinamomum zeylanicum in streptozotocin induced diabetes in Mice
Background: Diabetes is recognized as one of the leading causes of morbidity and mortality & representing as an emerging global epidemic worldwide. Diabetes and stroke both are the conditions which share various common t...
Antimicrobial analysis of Triphala and comparison with its individual constituents
Triphala, a well known ayurvedic formulation is used against number of ailments since ancient times. It consists of Emblica officinalis, Terminalia chebula and Terminalia bellerica in equal proportion. Triphala as a wh...
Synthesis, characterization and pharmacological evaluation of substituted 4-aryl thiazole-2-amino acetanilides
A series of novel 4-aryl thiazole-2-amino acetanilides (B1-B6) was designed and synthesized via the preparation of 2-amino 4-aryl thiazole (1) by acetophenone and thiourea which on subsequent condensation with α-chloroa...