SPECTROPHOTOMETRIC ESTIMATION OF CYCLOPHOSPHAMIDE IN CAPSULE DOSAGE FORM
Journal Title: Int J of Pharm Res & Analy - Year 2015, Vol 5, Issue 1
Abstract
A spectrophotometric method for the analysis of cyclophosphamide in pure form and in capsule has been developed using 0.1N HCl as solvent. The chromogen exhibited absorption maxima at 263 nm. Beer’s law was obeyed in the concentration ranges of 10-50 μg/ml. The proposed method was successfully applied for determination of the cyclophosphamide in their pharmaceutical formulations. The method is simple, precise and accurate and not having interference in adjutants in capsules.
Authors and Affiliations
Thangabalan B, , Harini A L , Manohar Babu S
Keywords
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