Spinal Leptomeningeal Metastasis Of Cerebral Glioblastoma Multiforme In A Child
Journal Title: Journal of Neurological Sciences-Turkish - Year 2005, Vol 22, Issue 2
Abstract
The spreading of cerebral glioblastoma multiforme into the spinal canal and causing clinical symptoms are seen rarely. An 11-year-old male patient was admitted to our clinic with headache. Cerebral MRI showed a contrast enhanced lesion in the occipital horn of the lateral ventricle which was approximately 3x4x3 cm in diameter. The tumour was totally resected. Pathological diagnosis of the tumour revealed glioblastoma multiforme. On control MRI there was not residual tumour. Cranial radiotherapy and chemotheraphy was applied. Five months later, he was admitted again to our clinic because of sudden onset of severe lumbago, and disability of walking. Spinal MRI demonstrated multifocal spread of glioblastoma multiforme, including intradural intramedullar spinal drop metastases at the level of cervico-thoracic vertebrae (between C7 and T10) and intradural lumbosacral region. Radiotherapy and chemotheraphy was not applied again. The patient with a mean follow up period of 5 months was uneventful, and he has been paraparesis for 6 months.
Authors and Affiliations
Aslan GUZEL, Mehmet TATLI, Ahmet DIRIER, Mustafa BOZBUGA, Cicek BAYINDIR
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