Sporadic Insulinoma In A 16-Yr-old Girl: A Rare Case Report and Review of Literature
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 10
Abstract
Insulinoma is rare pancreatic islet cell neuroendocrine tumor typically sporadic, solitary and benign. We report the case of sporadic insulinoma in 16-year-old girl who presented with chief complaints of loss of consciousness episode daily since 7 month associated with palpitation, tremors, and diaphoresis. Clinical examination and laboratory investigation suggestive of pancreatic insulinoma, then patient admitted for further workup. A fasting test of 48-hour was done and ceased within 3 hours due to occurrence of hypoglycemic symptoms. During the episode, blood was drawn and results showed low blood glucose level and high insulin, pro-insulin and C-peptide levels. The hypoglycemic symptoms were relieved by glucose administration and Whipple’s triad for insulinoma was achieved. Triple phase computed tomography scan whole abdomen showed mass lesion with of approx. 13×12 mm noted in neck of pancreas. Fat planes with adjacent structures maintained. Patient underwent laparoscopic enucleation of pancreatic tumor. Histopathological and immuno-histochemical examination of the pancreatic mass has confirmed neuroendocrine tumor (insulinoma). A post-operative 6-month follow-up showed resolution of hypoglycemic symptoms, normalized blood glucose, insulin, pro-insulin and C-peptide levels, and no evidence of recurrence.
Authors and Affiliations
Vikram Singh Sodha, Bhanu Kaushik, Shalu Gupta, Narendra Kumar, Bhanwar Lal Yadav
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