Squamous cell carcinoma of skin and primary adenocarcinoma of the colon: a case report with review of literature
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2016, Vol 4, Issue 5
Abstract
Colorectal adenocarcinoma may demonstrate familial association with cancers at other sites. Herein, we reported a case report with SCC of the skin and colon cancer in the West of Iran. On July 2015, a 44-year man referred to the Clinic of Gastroenterology with complaints of weight loss, anorexia, weakness, lethargy and mild persistent pain of right flank since 2 months ago. After colonoscopy, the pathology report showed adenocarcinoma of the colon. On August 2015 after ileocolectomy, he was treated with Xeloda and Oxaliplatin. On October 2015, one papule was appeared on the right buttock and then was grown and ulcerated. After 5 months, the size of it increased up to 7 cm. The pathology report of incisional biopsy showed well differentiated SCC with 4.5 mm tumor thickness. Although, Lynch Syndrome was not confirmed in our case with immunohistochemistry and genotyping association of adenocarcinoma of the colon with SCC of the skin with criteria such as rather young age of patient, right-side location, mucinous feature and tumor infiltration of lymphocytes may be suggestive for further evaluation of the patient and his family with low cost tests such as occult blood in areas which high cost tests are not available or can’t be used. Keywords: SCC of skin, Adenocarcinoma of colon, Case report
Authors and Affiliations
Mazaher Ramezani, Samane Danaei, Seyed-Hamid Madani, Masoud Sadeghi
Keywords
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