STABILITY EVALUATION OF TOPICAL OINTMENT COMPRISING CALCIPOTRIOL AND PREDNICARBATE
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2015, Vol 6, Issue 1
Abstract
Stability studies ensuring the maintenance of product quality, safety and efficacy throughout the shelf life are considered as pre-requisite for the acceptance and approval of any pharmaceutical product. The objective of present investigation was to study the stability of a two-compound ointment containing Calcipotriol and Prednicarbate formulated using polyoxypropylene – 15-stearyl ether and Vitamin E Acetate when stored at different conditions for specific duration of time. Stability on storage is an important aspect which ensures the dosage form can exert the effects it is supposed to exert for the duration of storage. Appearance, drug content, pH and microbiological parameters are the parameters that have been assessed under different temperature to evaluate the stability of the ointment. The data obtained from the stability study showed that this formulation is stable for the 6 months period when stored at real time conditions.
Authors and Affiliations
Jyoti Phatangare , Sharada Deore , Kundan Phatangare
Keywords
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- EP ID EP100256
- DOI 10.7897/2230-8407.06110
- Views 60
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