PHYTOCHEMICAL INVESTIGATION ON WITHANIA SOMNIFERA ROOT MARC GENERATED IN AYURVEDIC INDUSTRY
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2013, Vol 4, Issue 8
Abstract
Water extraction is a major process in Ayurvedic medicine manufacturing industry. This process involves water extraction of huge quantity of herbs, which culminates in the generation of large amount of marc or herbal residue. Usually the residue is either incinerated or converted to herbal manure. This paper investigates the marc of Withania somnifera roots obtained from Ayurvedic Industry for presence of valuable and potent bioactive phytochemicals. The chances of the phytochemicals getting altered by the process of prolonged heating is also looked into and found that no such genesis or degradation of phytochemicals leading to a new compound has occurred in the marc. As part of study, physicochemical analysis such as total ash percentage, acid insoluble ash percentage and extractive values are performed. Preliminary phytochemical analysis was carried out with different extracts, like hexane, ethyl acetate and methanol of both herb and marc which showed the presence of similar compounds. High Performance Thin Layer Chromatography finger printing and densitogram of hexane, ethyl acetate and methanol extracts of marc and herb showed that there was a reduction in the concentration of the actives in marc. The densitogram of ethyl acetate extract showed absence of certain prominent peaks in marc. In the case of methanol extract the prominent peaks were present in the marc and the concentration of some major actives were reduced in the hexane extract of marc.
Authors and Affiliations
Rajalakshmy M R, Sindhu A, Geetha G
Keywords
Related Articles
- EP ID EP136033
- DOI 10.7897/2230-8407.04844
- Views 120
- Downloads 0
ANTIOXIDANT, IMMUNOMODULATORY AND ANTICANCER ACTIVITIES OF EMBLICA OFFICINALIS: AN OVERVIEW
Emblica officinalis (Amla) is traditionally used for several diseases, and it is believed to increase the defense against diseases. It is particularly used for the treatment of cancer, diabetes, liver disorders, heart di...
DEVELOPMENT AND VALIDATION OF RP-UPLC ANALYTICAL METHOD FOR SIMULTANEOUS ESTIMATION OF EMTRICITABINE, RILPIVIRINE, TENOFOVIR DISOPROXIL FUMARATE AND ITS PHARMACEUTICAL DOSAGE FORMS
Developing a single analytical method for estimation of individual drug from a multidrug composition is a very challenging task. A simple, rapid, precise, and reliable simultaneous RP -UPLC method was developed for the s...
THERAPEUTIC ASPECTS OF GOLDENSEAL
Goldenseal, commonly known as yellow puccoon has wide therapeutic activity. The bioactive components present are isoquinoline alkaloids, hydrastine, berberine and canadine. Berberine is used to treat heart failure also h...
IN VITRO ANTIMICROBIAL AND ANTIOXIDANT ACTIVITY OF GINKGO BILOBA BARK EXTRACT
Ginkgo biloba also called as Maidenhair Tree, belongs to the family Ginkgoaceae. In this study, the hydro-Methenolic extract from bark of Ginkgo biloba was screened for their in vitro antimicrobial and antioxidant activi...
PREPARATION AND EVALUATION OF MUCOADHESIVE MICROCAPSULES OF IBUPROFEN FOR CONTROLLED RELEASE
The aim of this study was to prepare and evaluate microcapsules containing ibuprofen employing sodium alginate in combination with mucoadhesive polymers namely methylcellulose, Hydroxypropylmethylcellulose and sodiumcabo...