STABILITY STUDIES OF RIBAVIRIN SYRUP
Journal Title: Indo American Journal of Pharmaceutical Research - Year 2011, Vol 1, Issue 5
Abstract
Ribavirin is an antiviral agent commonly used for the treatment of severe acute respiratory syndrome. The present study investigated the stability of marketed oral Ribavirin syrup. The syrup was subjected to accelerated stability testing at 40°C and 75% RH for 6 months as per ICH guidelines. HPLC method to estimate Ribavirin was developed and validated. Employing a validated high-performance liquid chromatographic method, the Ribavirin content of the syrup has been demonstrated to exhibit changes throughout the storage period. No physical changes was observed in syrup suggesting that it remained physically stable, but effected the chemically stability of syrup under the stated conditions.
Authors and Affiliations
Dhanyakumar Chougule, Nilofar Naikwade
Keywords
Related Articles
- EP ID EP221881
- DOI -
- Views 153
- Downloads 0
REMOVAL OF FLUORIDE FROM AQUEOUS SOLUTION USING FIRED CLAY SOIL PILLARED WITH TEA LEAF ASH COMPONENTS
Abstract This study reports on the adsorption of fluoride ion from aqueous solutions by using fired clay soil, pillared with tea leave ash components. The potential of low cost material fired clay soil and fired clay soi...
Development and evaluation of Propranolol hydrochloride buccal mucoadhesive gel using Natural Mucoadhesive Agent obtained from the Fruits of Ficus carica L.
Buccal delivery is considered to be an important alternative to the peroral route for the systemic administration of drugs. The paper describes formulation of buccal mucoadhesive gel from Ficus carica mucilage using pror...
THE ROLE OF BACTERIOCINS IN THE CONTROLLING OF FOODBORNE PATHOGENS
Abstract Bacteriocins are antimicrobial peptides or proteins produced by strains of diverse bacterial species. The antimicrobial activity of this group of natural substances against food borne pathogenic, as well as spoi...
PREVALENCE OF ANTIBIOTIC USE IN PEDIATRIC INFECTIONS AND ENHANCING OPTIMAL ANTIBIOTIC UTILIZATION THROUGH PATIENT COUNSELING
Abstract AIMS: To identify the prevalence of antibiotic use in pediatric infections and to counsel the patients or their representatives on the optimal use of antibiotics. METHOD: The study will be conducted in Governmen...
BIOSYNTHESIS OF SILVER NANOPARTICLES AND CHARACTERIZATION
Abstract In current science, nanotechnology has been thriving at a tremendous rate in all aspect of Science and Technology. It deals with between 1 to100 nm sizes of nanoparticles in at least one dimension and involves i...