Stan czynnościowy narządu słuchu w zespole nerczycowym w przebiegu pierwotnej glomerulopatii u dzieci
Journal Title: Otolaryngologia Polska - Year 2008, Vol 62, Issue 2
Abstract
Nephrotic syndrome (NS) is connected with an increase of glomeral permeability. It generates numerous, reversible electrolic and biochemical disturbances. The aim of the work was complex evaluation of hearing organ in children in the course of NS. Material. 28 children aged from 7 to 17 years suffering from primary glomerulopathy, without renal failure and 28 healthy children in the relative age (control group). Method. In children with NS hearing tests (pure tone audiometry, impedance audiometry, BAEP, DPOAE) have been performed twice: in acute phase and in non-symptomic phase. Such parameters as total protein, albumines, globulins, cholesterol, sodium, potassium, calcium, magnesium were evaluated. Results. In oedematous stage the concentration of total protein, albumines and calcium were signifi cantly decreased and the concentration of cholesterol was increased. Children with NS presented much worse hearing than healthy subjects, even after the symptoms dissapeared. in acute phase such parameters of BAEP as peak III latency and interpeak I-III interlatency were elongated and DPOAE values were decreased. In normal phase BAEP parameters were similar to those in normal group but DPOAE parameters were still much worse than in healthy children. Some of the biochemical parameters correlated with hearing results in children with NS. Conclussions. Hearing organ in children with NS in the course of chronic glomerulopathy is signifi cantly worse than in healthy children. It is probably connected with repeated biochemical and electrolytic disturbances that cause partly reversible alterations in the cochlea, acoustic nerve and brain stem. It may be also caused by ototoxic drugs.
Authors and Affiliations
Krystyna Orendorz-Frączkowska, Anna Medyńska, Agnieszka Jabłonka, Wojciech Gawron
Keywords
Related Articles
- EP ID EP51451
- DOI -
- Views 117
- Downloads 0
Early surgical reuision as a saluage procedure in the anterolateral thigh flap failure preuention — case report
Microsurgical free flaps are considered state of the art in head and neck reconstruction after composite tumor resections. The anterolateral thigh (ALT) flap is frequently used in ablative head and neck surgery, providin...
Gruźlica krtani u pacjentów leczonych w klinice otolaryngologii – opis dwóch przypadków
Tubercular infection is still one of the most serious health and social problems. It’s been estimated that one-third of the population is infected with Koch’s bacillus. More than 90% of overall morbidity of tuberculosis...
Neoplasms of the salivary glands: analysis of 727 histopathological reports in a single institution
Introduction: Salivary gland tumors comprise three to ten percent of all head and neck tumors. The parotid gland is affected most often (64-80%). Malignant tumors constitute a minority, occurring in 15-32% of cases. Pleo...
Objawy otologiczne w świetle najnowszej wiedzy o ziarniniaku Wegenera
Ocena odsetka limfocytów B z ekspresją koreceptorów CD40, CD22 i CD72 w przerosłych migdałkach gardłowych dzieci chorych na wysiękowe zapalenie ucha
Introduction: In hypertrophied adenoid lymphocytes B make up about 60% all lymphocytes. When the lymphocytes B come in interaction with antigens this membranes signal be passed through their receptor (BCR) to interior of...