Standardization and Comparative Analysis of Metalloid Based Novel Siddha Preparation Thurusu
Journal Title: INTERNATIONAL JOURNAL OF CURRENT RESEARCH IN MEDICAL SCIENCES - Year 2018, Vol 4, Issue 5
Abstract
Siddha system of medicine is a pioneering practice among the Indian system of traditional medicine. Siddha is a traditional art of healing which provided therapeutic benefits to the mankind since several centuries. Siddhars are considerably an ancient siddha physicians systematically formulated the siddha formulation with the added medicaments from herbs, minerals, metals and even with ores. Due to increase need of globalization and with other regulatory necessities it is now a days becomes highly mandate that the drug should proves its standard, genunity and safety before prescribing the same to the humans. Hence the main aim of the present investigation is to systematically standardize and make a comparative evaluation of unpurified thurusu (UPT) and purified thurusu (PT) a metalloid based novel siddha preparation. The results obtained from the physicochemical evaluation reveals that the loss on drying value of UPT and PT was found to be 28.23 and 3.56%w/w. The total ash value of UPT and PT was 47.51 and 22.89%w/w. In which the acid insoluble ash value of UPT (0.0961 % w/w), PT (0.2174% w/w). The water soluble ash value of UPT and PT was 22.54 and 1.708%w/w respectively. The results of water soluble extractive of UPT were 71.45% w/w and for PT it was 22.49%w/w. Similarly the alcohol soluble extractive value of UPT and PT was found to be 1.673% and 22.52%w/w. The percentage of copper present in UPT was 23.36%w/w and for PT it was 12.67%w/w, whereas the total percentage of sulphur present in UPT was 13.57%w/w and for PT it was 4.403%w/w. It was concluded from the results of the present investigation that there is significant change in the physicochemical data’s of unpurified and purified form of thurusu with respect to significant decrease in the values obtained from LOD, total ash, extractive value and also with total percentage of copper and sulphur. Hence it as concluded that the purified thurusu complies with the prescribed standard and further the standardization values of PT are within the limit to confirm the genunity of the preparation.
Authors and Affiliations
R. Dhanalakshmi1 , A. Sureka2 R. Madhavan3
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