Standardization of clinical laboratory data and reference intervals
Journal Title: Journal of Analytical Bio-Science - Year 2011, Vol 34, Issue 3
Abstract
For clinical laboratory data to be utilized in the diagnosis and prevention of disease, their reliability must be verified. To ensure the reliability of routine test data in all laboratories, it is necessary for it to be consistent with the traceability chain for each constituent, and for the values to be transferred from that measurement system appropriately. The nationwide standardization of measurement data by the utilization of both reference and control materials will enable us to ensure the widespread and long-term reliability of clinical laboratory data. To achieve this system-based consistency, the laboratories must verify the accuracy of test data, so that the reference interval of laboratory data for disease screening can be shared by different institutes. Resarding the improved reliability of measurement values, two new reference-intervals, studies have beenpublished; one by the Japanese Association of Medical Technologists, which establishes the reference intervals that can be shared by all clinical laboratories, and another that addresses the research results of differences between areas in Asian districts regarding the reference values of clinical tests. Thus, the latest knowledge about the standardization of both reference intervals and measurement values will be will be widely disseminated.
Authors and Affiliations
Shigemi Hosogaya
Keywords
Related Articles
- EP ID EP119147
- DOI -
- Views 81
- Downloads 0
The circadian rhythm of glycosylated compounds: HOMA-R and HOMA-β
Although there is some difference among an individuals, it is well known that circadian changes are present in nearly all life throughout our bodies. It is important to understand interindividual variations in order to d...
Current status of metrological traceability and measurement uncertainty in clinical laboratories
Standardization is the most important issue in laboratory medicine. ISO has established the metrological traceability in laboratory medicine as International Standard 17511. Many countries have studied standardization pr...
Albumin-like reactivity of amphoteric and cationic surfactants toward BCG color reagents
Bromocresol Green (BCG) dyes exist as an equal mixture of undissociated (λmax 450 nm) and dissociated (λmax 620 nm) dye forms in acid solutions. In BCG color reagents for measuring serum albumin, color development of th...
The present state and problems of a Global Clinical Trial Study
A Global Clinical Trial Study is an important trial for drug rag cancellations. The environment in Japan to smoothly advance a Global Clinical Trial Study is now underway. As a result, the number of Global Clinical Trial...
[i]In vitro[/i] and [i]in vivo [/i]studies of the anti-immortalized effects of Hohrokutake ([i]daedalea dickinsii yasuda[/i]) extract on the immortalized cell line established from bovine granulosa cells
1. [i]In vitro[/i] experiment The growth of immortalized cells was found to perfectly inhibit Eagle's medium containing a small amount of the extract. 2. [i]In vivo[/i] experiment The immortalized cells were injected...