Annual school health check-up and hyperuricemia and lifestyle-related diseases among Japanese school children
Journal Title: Journal of Analytical Bio-Science - Year 2011, Vol 34, Issue 5
Abstract
In recent years, serum uric acid (SUA) levels have been shown to be strongly associated with the presence of cardiometabolic abnormalities, such as abdominal obesity, hypertension, hypertriglyceridemia, low high-density lipoprotein cholesterol, and impaired glucose tolerance, in adults. Using a school-based sample of Japanese junior high school students obtained at the annual school health check-up, we demonstrated a strong association between SUA and the presence of multiple cardiometabolic risk factors in boys. The optimal cutoff points of SUA to predict multiple risk factors by receiver operating characteristics curve analysis were identified as 6.4 mg/dL for boys and 4.9 mg/dL for girls. These results might be useful for the development of educational programs on prevention of lifestyle-related diseases, and contribute to the setting of new reference values of SUA based on the presence of multiple cardiometabolic risk factors in the Japanese population of junior high school students.
Authors and Affiliations
Minoru Hongo
Keywords
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