Staphylokinase: A Potent Thrombolytic Agent
Journal Title: International Journal of Engineering and Science Invention - Year 2018, Vol 7, Issue 1
Abstract
As the incidences of Cardio Vascular Diseases (CVDs) is increasing all over the world, the deaths associated with CVDs have also, been on the rise. WHO estimates a total of 17.3 million deaths due to CVD every year which is set to rise to 24 million by 2030. Myocardial Infarction (MI) is one of the deadliest among CVDs group. An alarming number of people are falling prey to MI and most of them need a quick clinical intervention. Out of the many surgical and chemical treatments under development, thrombolytic enzymes have a huge potential and a major role to play. Staphylokinase (SAK) is one such enzyme that has the potential to be used as a thrombolytic agent. SAK is small, less immunogenic and doesn’t cause systemic bleeding. This review discusses the basic aspects of thrombosis, CVDs, mechanism and the role of Staphylokinase to be used as a potent thrombolytic agent.
Authors and Affiliations
Afshan Sumera, Payel Chaudhury, Shafiul Haque, Pradipta Saha, Debarati Paul, Arshad Jawed
Keywords
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