Stem Cell Treatment for Acute Lymphoblastic Leukemia in Adults
Journal Title: Journal of Regenerative Medicine & Biology Research - Year 2024, Vol 5, Issue 2
Abstract
Stem cell therapy used to treat Acute Lymphoblastic Leukemia in adults (ALL) has been one of the more promising uses of stem cells and has large implications on the survival rate of adults with ALL. While the survival rate of ALL remains relatively low at an estimated 20% to 30% in adults, stem cell as an adjunct therapy has shown promising results. Historically, ALL has a high rate of recurrence in adults and one study aims to assess the effectiveness of hematopoietic stem cell therapy in diminishing the rates of recurrence. Stem cell therapy for blood diseases is most found in the form of an allogeneic bone marrow transplant, which includes transplantation of HSCs from a donor. It can help to stimulate the body to produce healthy blood cells and thereby keep the disease at bay. The study concluded that HSCT increases the survival rate of adults with ALL and that it should be considered if a patient has a viable donor available. We see that multiple other studies come to similar conclusions, such as one study that found increased long-term disease-free survival can be achieved through stem cell therapy. A culmination of incredible research excites the idea of an extraordinary step forward in helping to cure those suffering from acute lymphoblastic leukemia and improve long-term, disease-free survival.
Authors and Affiliations
Katie Scott1, Vincent S Gallicchio1*
Keywords
Related Articles
- EP ID EP742463
- DOI https://doi.org/10.46889/JRMBR.2024.5205
- Views 17
- Downloads 0
Expression of Neuron Specific Neuronal Nuclei Protein (NeuNNP) by AAV2 Shows Diagnosis Ability in Spinal Cord Injury Using Neural Stem Cells
Fibroblast Growth Factor (FGF) shows promising therapy for Spinal Cord Injury (SCI). Neural stem transplantation has been on the role implementing tactics to repair SCI. Considering the hostile hypoxia condition in SCI...
Utilizing Adipose Tissue-Derived Stem Cell Strategies for Obtaining Regeneration of Respiratory Tract Fistulas-A Systematic Review
Fistula of the respiratory tract represent an aberrant communication or passage among the respiratory system as well as the digestive tract or the nearby organs. They might originate congenitally or more commonly, iatr...
Suprachoroidal Umbilical Cord-Derived Mesenchymal Stem Cell Transplantation for the Regeneration of Glaucomatous Optic Neuropathy: A Preliminary Investigation
Objective: This preliminary research presents clinical findings from patients with advanced Glaucomatous Optic Neuropathy (GON) who underwent transplantation of Umbilical Cord-Derived Mesenchymal Stem Cells (UCMSCs) into...
A Regenerative Interventional Approach to the Management of Degenerative Low Back Pain
Objective: Low back pain has been strongly related to the degenerative process of the spine, especially the degeneration of the intervertebral disc and facet joints. The main procedures for the management of low back pai...
Bioregenerative Applications of the Human Mesenchymal Stem Cell- Derived Secretome: Part-I
Mesenchymal stem cells hold many therapeutic benefits in treating diverse disease states, but autologous requirements, high costs, lack of standardization and other factors limit their widespread application. Additionall...