Steroid-induced diabetes in oncology
Journal Title: OncoReview - Year 2012, Vol 2, Issue 2
Abstract
Patients with neoplasms belong to the group of higher risk for developing steroid-induced diabetes. The rules of diagnosis of this form of diabetes do not differ from others of its type, but the course and treatment differ significantly from the clinical picture observed in type 1 and 2. It results from different schemes of glicocorticotherapy, differentiated state of the patient dependent on tumor stage and presence of comorbidities. However, note that in a patient with hyperplastic process, diabetes can occur regardless of the administration of diabetogenic agents, which can be exemplified by the presence of diabetes or pre-diabetic status in a patient with pancreatic cancer. Another clinical situation occurs if the patient with diabetes has to be treated with glicocorticosteroids due to neoplasmatic process. It should be emphasized as an inverse relationship eg. stimulation of tumor growth by processes occurring in type 2 diabetes particularly with concomitant visceral obesity. Such a patient will be more prone to induce hyperglycaemia during glicocorticotherapy. The atricle presents the practical aspects of treatment of hyperglycemia in glicocorticotherapy.
Authors and Affiliations
Beata Mrozikiewicz-Rakowska
Keywords
Related Articles
- EP ID EP53155
- DOI -
- Views 225
- Downloads 0
Postępy w leczeniu szpiczaka mnogiego w roku 2012
Szpiczak mnogi (MM, multiple myeloma) nadal jest uznawany za rozrostową nieuleczalną chorobę nowotworową. W roku 2012 opublikowano ok. 100 artykułów pokazujących postępy w jego leczeniu. W badaniach podstawowych zwrócono...
The evaluation of the efficacy and toxicity of targeted treatment in non-small cell lung cancer patients – single centre experience
Introduction: Tyrosine kinase inhibitors (TKI) are the standard of treatment in patients with advanced non-small cell lung cancer (NSCLC) with EGFR (endothelial growth factor receptor) gene activating mutation. Objecti...
Progress in treatment of multiple myelomain year 2012
A role of JAK in the pathogenesis of Philadelphia negative myeloproliferative neoplasms. Target therapy possibilities
In recent years a significant progress has been made in understanding of the pathogenesis of myeloproliferative neoplasms, especially the one with mutation in JAK2 gene. In 2005 several study groups confirmed the presenc...
Znaczenie badań molekularnych w kwalifikacji do terapii I linii erlotynibem chorych na NDRP na podstawie wyników badania EURTAC
W latach 2010–2011 pierwszy inhibitor kinazy tyrozynowej EGFR (IKT EGFR) – gefitynib uzyskał w wielu krajach rejestrację do leczenia w I linii chorych na zaawansowanego i miejscowo zaawansowanego niedrobnokomórkowego rak...