Steroid-induced diabetes in oncology
Journal Title: OncoReview - Year 2012, Vol 2, Issue 2
Abstract
Patients with neoplasms belong to the group of higher risk for developing steroid-induced diabetes. The rules of diagnosis of this form of diabetes do not differ from others of its type, but the course and treatment differ significantly from the clinical picture observed in type 1 and 2. It results from different schemes of glicocorticotherapy, differentiated state of the patient dependent on tumor stage and presence of comorbidities. However, note that in a patient with hyperplastic process, diabetes can occur regardless of the administration of diabetogenic agents, which can be exemplified by the presence of diabetes or pre-diabetic status in a patient with pancreatic cancer. Another clinical situation occurs if the patient with diabetes has to be treated with glicocorticosteroids due to neoplasmatic process. It should be emphasized as an inverse relationship eg. stimulation of tumor growth by processes occurring in type 2 diabetes particularly with concomitant visceral obesity. Such a patient will be more prone to induce hyperglycaemia during glicocorticotherapy. The atricle presents the practical aspects of treatment of hyperglycemia in glicocorticotherapy.
Authors and Affiliations
Beata Mrozikiewicz-Rakowska
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