Striking Visualization of Diffuse Congenital Nesidioblastosis on Ga-68 DOTATATE PET/CT
Journal Title: Molecular Imaging and Radionuclide Therapy - Year 2019, Vol 28, Issue 2
Abstract
“Nesidioblastosis”, later renamed as “persistent hyperinsulinemic hypoglycemia of infancy” presents as either focal or diffuse neo-differentiation of pancreatic Langerhans islet cells from the ductal epithelium. Differentiation of focal disease from diffuse involvement is crucial for optimal disease management. The current methods used to differentiate the two forms pre-operatively are invasive techniques. The definite role of imaging modalities to differentiate diffuse versus focal form has not yet been proven. Herein, we report a 15 day-old infant having diffuse nesidioblastosis, successfully demonstrated by Ga-68 DOTATATE positron emission tomography/computed tomography imaging that was histopathologically confirmed.
Authors and Affiliations
Fevziye Canbaz, Murat Aydın, Bilge Can Meydan, Meltem Ceyhan Bilgici, Ender Arıtürk
Keywords
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- EP ID EP591720
- DOI 10.4274/mirt.galenos.2018.38039
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