<strong>Bioprotective Potential of Bacteriocinogenic <em>Enterococcus gallinarum</em> Strains Isolated from Some Nigerian Fermented Foods, and of Their Bacteriocins</strong>
Journal Title: Polish Journal of Microbiology - Year 2014, Vol 63, Issue 4
Abstract
[i]Enterococcus gallinarum [/i]strains isolated from some Nigerian fermented foods were found to produce bacteriocins. The bacteriocins had a broad spectrum of activity against both Gram positive and negative bacteria. The effects of the bacteriocins and bacteriocinogenic organisms on [i]Staphylococcus aureus[/i] infections in rats were evaluated.[i] Sprague-Dawley[/i] rats were infected with [i]S. aureus[/i] MTCC 737 and treated with [i]E. gallinarum [/i]T71 and different concentrations of the bacteriocins from [i]E. gallinarum [/i]W211 and T71. [i]Staphylococcus aureus[/i] infection caused significant upregulation of aspartate aminotransferase and alanine aminotransferase levels in sera of the infected rats. Moreover, gelatin zymography revealed that infected gastric tissues showed elevated matrix metalloproteinase-9 activity. Bacteriocin treatments reduced the MMP-9 activity and inhibited the expressions of both Tumour Necrosis Factor Alpha (TNF-α) and Interleukin-1 Beta (IL-1β), pointing to a potential role of the bacteriocins in attenuating inflammatory responses to [i]Staphylococcus aureus[/i] infection. Gastric and GIT damage caused by Staphylococcal infection were reduced in the [i]Enterococcus gallinarum [/i]T71 and bacteriocin-treated groups. We conclude that these bacteriocins may have useful biomedical applications.
Authors and Affiliations
Iyabo C. Oladipo, Abiodun I. Sanni, Writachit Chakraborty, Somnath Chakravorty, Sayantan Jana, Deep S. Rudra, Ratan Gacchui, Snehasiktas Swarnakar
Keywords
Related Articles
- EP ID EP59267
- DOI -
- Views 87
- Downloads 0
<strong>Prevalence of Parasitic Contamination in Salad Vegetables Collected from Supermarkets and Street Vendors in Amman and Baqa’a – Jordan</strong>
One of the main ways in transmitting parasites to humans is through consuming contaminated raw vegetables. The aim of this study was to evaluate the prevalence of parasitological contamination (helminthes eggs, [i]Giardi...
Molecular Characterization of Shiga Toxin-Producing Escherichia coli Strains Isolated in Poland
Shiga toxin-producing Escherichia coli (STEC) strains also called verotoxin-producing E. coli (VTEC) represent one of the most important groups of food-borne pathogens that can cause several human diseases such as hemorr...
Characterization of Extended-Spectrum-β-Lactamases Produced by[i] Escherichia coli [/i]Strains Isolated from Dogs in Poland
[i]Escherichia coli[/i] is a common cause of infections in companion animals. In recent years the increasing prevalence of resistance to β-lactams, including extended-spectrum cephalosporins, antimicrobials frequent...
Gene Expression during BTEX Biodegradation by a Microbial Consortium Acclimatized to Unleaded Gasoline and a Pseudomonas putida Strain (HM346961) Isolated from It
Pseudomonas putida strain (HM346961) was isolated from a consortium of bacteria acclimatized to unleaded gasoline-contaminated water. The consortium can efficiently remove benzene, toluene, ethylbenzene and xylene (BTEX)...
Recovery of Gram-Positive Cocci and Candida albicans from Peroxygens/Silver-Based Disinfectants
Neutralization method evaluation is an important first step in disinfectant validation study program. It is, also, crucial in the assessment of the efficiency of microbial recovery media in the presence of residual bioci...