STUDIES OF BIOCHEMICAL PARAMETERS IN BREAST CANCER WITH AND WITHOUT<br /> METASTASIS
Journal Title: Indian Journal of Clinical Biochemistry - Year 2004, Vol 19, Issue 1
Abstract
The study includes 102 confirmed cases of carcinoma breast with and without metastasis and 25 healthy non-pregnant females. They were evaluated for blood levels of Ferritin, GSH, LDH, ALP, GGT and Hb before and 21 days after mastectomy. A significant increase (p<0.001) was observed in ferritin, LDH and GSH levels in cancer patients without metastasis in comparison to normal control subjects. Patients with metastasis had further elevated (p<0.001) levels of Ferritin, ALP and GGT as compared to non-metastatic patients. Mastectomy in both the cases i.e. with and without metastasis resulted in non-significant decrease in all the biochemical parameters suggesting that longer follow up could confirm post surgery decrease in the biochemical parameters. The results of the study suggest cost effective, usefulness of Ferritin, ALP, GGT and GSH / Hb ratio in differentiating breast cancer patients with and without metastasis which can be assayed in smaller laboratories.
Authors and Affiliations
Sandhya Mishra , D. C. Sharma , Praveen Sharma
Keywords
Related Articles
- EP ID EP118551
- DOI -
- Views 99
- Downloads 0
Isolation and Culture of Leydig Cells from Adult Rats
SIALIC ACID IN CARDIOVASCULAR DISEASES
Sialic acid, the acylated derivatives of 9-carbon sugar neuraminic acid, present as terminal component of oligosaccharide chains of many glycoproteins and glycolipids, has been recognized to be involved in the regulati...
EFFECT OF OCIMUM SANCTUM (TULSI) AND VITAMIN E ON BIOCHEMICAL PARAMETERS AND RETINOPATHY IN STREPTOZOTOCIN INDUCED DIABETIC RATS
This study was carried out to see the effect of the aqueous extract of Ocimum sanctum Linn (Tulsi) with Vitamin E on biochemical parameters and retinopathy in the streptozotocin-induced diabetic albino male rats. Adult...
RAISED SERUM HOMOCYSTEINE LEVELS IN PATIENTS OF CORONARY ARTERY DISEASE AND THE EFFECT OF VITAMIN B12 AND FOLATE ON ITS CONCENTRATION
Homocysteine(Hcy) has been implicated as a novel risk factor of Coronary Artery Disease (CAD) among Asian Indians, but many studies done in India failed to reveal any direct correlation. It has also been reported that...
DETECTION OF ENZYMES DEHYDROGENASES AND PROTEASES IN BRUGIA MALAYI FILARIAL PARASITES
Lymphatic filariasis caused mainly by infection from W. bancrofti and B. malayi remains a major cause of clinical morbidity in tropical and subtropical countries. Analysis of B.malayi mf, infective larval and adult wor...