Study of Acute Kidney Injury in Critically Ill Children Admitted To Paediatric Intensive Care Unit of a Tertiary Centre
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 10
Abstract
Acute Kidney Injury (AKI) refers to a reversible accumulation of urea, creatinine and nitrogenous waste products and disturbances in maintenance of fluid and electrolyte homeostasis. The incidence of AKI continues to increase in the Paediatric age group particularly in critically ill children with the etiology shifting from primary renal disorders to multifactorial cause. A prospective observational study was done with 342 children aged between 1-12 years, admitted in Paediatric Intensive Care Unit (PICU) of Institute of Child Health & Research Centre, Madurai Medical College, Madurai during July 2015 to June 2016. Aim of the study was to determine the incidence, clinical profile and outcome of AKI in critically ill children using AKIN staging. The overall incidence of AKI among critically ill children was 31%. The mortality rate was 42.5% and 19.7% patients with AKI had partial renal recovery at the time of discharge. 26.4% patients required renal replacement therapy (RRT). Infectious causes 56.6% (Sepsis, Meningoencephalitis, Bronchopneumonia) dominated the etiological profile. Incidence of AKI is high in critically-ill children. AKI continues to be associated with adverse outcomes, including high mortality and partial renal recovery
Authors and Affiliations
D Rajkumar MD, V Jakanattane MD, M Kulandaivel MD
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