Study of ADA Levels in Cerebrospinal Fluid In Relation To Stages of Tuberculous Meningitis And Prognostic Significance of Staging in Tuberculous Meningitis.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 5
Abstract
Introduction: Tuberculous meningitis is a chronic meningeal infection by Mycobacterium tuberculosis characterized by fever, headache, nausea, vomiting, various levels of conciousness, siezures and raised intra cranial pressure. Materials and methods: The present study "study of ADA levels in cerebrospinal fluid in relation to stages of tuberculous meningitis and prognostic significance of staging in the patients" was carried out in the Department of Medicine, Rajendra Institute of Medical Sciences, Ranchi. • Study Design:- Prospective observational study • Sample Size:- 118 • Study Period:- Sept. 15 to Aug. 16 Results: Increased levels of CSF ADA was found in all cases of tuberculous meningitis(>6mg/dl). Mean level of CSF ADA was higher in MRC stage III (14.97±1.45) than in stage I (9.22±1.45). Mortality was also higher in stage III (20.6%). Conclusion: CSF ADA levels correlate with stage of disease at time of presentation as well as outcome and can be used as a prognostic indicator. Late stage of presentation along with raised CSF ADA levels have bad prognosis and poor chances of survival.
Authors and Affiliations
Dr. Chandra Bhushan Sharma, Dr. Shiny Kumari Khess, Dr. Rishi Tuhin Guria
Keywords
Related Articles
- EP ID EP597092
- DOI 10.9790/0853-160503120124.
- Views 67
- Downloads 0
Study of Neonatal Morbidity and Mortality in Very Low Birth Weight Neonates Admitted In Neonatal Intensive Care Unit in a Tertiary Care Centre
Background In recent trends, there is increasing number of babies born with very low birth weight. These VLBW babies are at risk of developing hypoglycemia, sepsis, hyperbilirubinemia, respiratory distress when compared...
Cerebral Venous Sinus Thrombosis: A Rare Complication of Cryptococcal Meningitis in HIV/AIDS Patient
.
Prevalence Of Adverse Events Related To Blood Transfusion At Tertiary Care Center Of Central India.
Background: Although blood transfusion is an essential part of medical treatment but it is also associated with significant clinical risks due to blood components’ allogenic origin. In recent testing facilities have lowe...
Non Operative Management in Blunt Injury Abdomen, Our Experience at a Tertiary Centre – A Case Series
Trauma is one of the leading causes of mortality at all age group. Blunt trauma to abdomen is one of the leading cause of death in young. BAT can remain silent after initial injury only to present later with clinical det...
A Case Study on Assessment of the Role of Different MRI Sequences and Contrast in Determining Tumor Margins in Musculoskeletal Tumors
MRI is the most useful investigation following plain x-rays in the detection and further evaluation of both bone and soft tissue sarcomas. The multiplanar capability, combined with the excellent soft tissue contrast and...