Study of amniotic membrane transplantation in the treatment of ocular injuries
Journal Title: International Journal of Biomedical and Advance Research - Year 2015, Vol 6, Issue 9
Abstract
Amniotic membrane is the innermost layer of the placental membrane and consists of a thick basement membrane and an avascular stroma.It can be used as a substrate to replace the damaged mucosal surface, and has recently been used successfully for reconstructing corneal and conjunctival surface damaged by various ocular surface disorders including chemical and thermal burns. The present study was undertaken in department of ophthalmology at Ashwini Rural Medical College and Research Center, Kumbhari, Solapur between 1at Jan 2013 to 31 Dec 2014, that is over a period of 2 years to know amniotic membrane transplantation as a treatment modality in the treatment of ocular injuries. After taking written informed consent from the patients and following standard operating procedures, a total of 40 patients were included in the study, non consenting patients were not included in the study. Conclusions: amniotic membrane transplantation is an effective way of treating ocular and thermal injuries in the acute stage. Such an acute intervention can break the vicious cycle leading to the progressive melting or scarring sequelae in the chronic stage. Amniotic membrane transplantation is more effective in preserving the anatomical as well as the functional structure of the conjunctival and corneal surface in terms of decreased corneal vascularisation, preventing conjunctivalization of the cornea, improved tear film status and preventing fibrosis in mild grade II to moderate (grade III) burns but cannot do so in severe (grade IV) burns with total limbal deficiency.
Authors and Affiliations
Manjunath Patil, Leena Ambarkar
Keywords
Related Articles
- EP ID EP354979
- DOI 10.7439/ijbar.v6i9.2557
- Views 82
- Downloads 0
An Outbreak of Dengue in Patna, Bihar: A study of 60 cases and review of literature
Background: Dengue virus belongs to familyFlaviviridae, having four serotypes that spread by the bite of infected Aedes mosquitoes. Materials and methods: Dengue positive cases from June to December of two constitutive...
Schwannoma of the thyroid gland A continued preoperative diagnostic dilemma
Non epithelial tumors of the thyroid glands are extremely rare, representing <1% of all thyroid tumors.(1) These tumors most often mimic a thyroid nodule. A case of Schwannoma of the thyroid gland which was diagnosed on...
Comparison of total laparoscopic Hysterectomy versus vaginal hysterectomy for benign non prolapsed uterus
Background: Vaginal hysterectomy is a well established and time tested procedure which is being done since the last 150 years and thus has been refined to a great degree, but it has been less successful due to lack of ex...
A study on the variations of arterial supply to adrenal gland
Introduction: Adrenal glands are richly vascular and get their arterial supply by means of three arteries namely superior, middle, inferior suprarenal arteries. The inferior phrenic artery gives off the superior branch,...
Congenital epulis in new born: a case report
Congenital epulis also known as Neumanns tumor, is a rare lesion of newborn. It is usually benign in nature. A newborn baby girl weighing 2100 gram was found to have a solid mass arising from the anterior ridge of the ma...