Study of Association between Platelet Function and Anthropometry of Blood Donors in a Single Institution
Journal Title: International Blood Research & Reviews - Year 2016, Vol 6, Issue 4
Abstract
Objective: To determine the association between obesity indices e.g. body mass index, waist circumference and platelet function in healthy blood donors. Methodology and Procedures: A cross-sectional study conducted on 100 healthy blood donors in Transfusion Medicine Department of King George’s Medical University, Lucknow. Subject selection based on inclusion and exclusion criteria. Anthropometric measures were recorded and sample of blood taken after blood donation and platelet count and platelet release test performed by specific method. Collected data analysed by Student’s t tests to assess the associations. Results: According to body mass index, 44% subjects have normal BMI and remaining 27% and 24% of the subjects have BMI within range from 23 to 24.9 and >25 respectively. Subjects based on waist circumference, 54% of subject have WC <85.9 cm and 21% of the subject have WC >90 cm. platelet count shows significant association with body weight and waist circumference of the healthy blood donor subject. However, no significant correlation was found between platelet function (Platelet release test) and anthropometric variables. Conclusion: Anthropometric variables like body weight, body mass index, and waist circumference can give a quantitative idea of platelet function including platelet count in blood of normal healthy donors.
Authors and Affiliations
Narsingh Verma, Somesh Raju, Sunita Tiwari, Tulika Chandra, Rina Kumari, Kshitij Bhardwaj
Keywords
Related Articles
- EP ID EP242779
- DOI 10.9734/IBRR/2016/28567
- Views 109
- Downloads 0
Lenalidomide, p53 and del(5q) Myelodysplastic Syndrome: Ribosome Stress Relief
Whereas deletions involving the long arm of chromosome 5 are among the most common chromosomal abnormalities in myelodysplastic syndrome (MDS), isolated del(5q) MDS, which includes the 5q- syndrome, is rare and character...
Determination of Platelet and White Blood Cell Counts from Peripheral Blood Smear: An Indispensable Method in Under-resourced Laboratories
Objective: Blood smear examination serves as a quality control tool in verifying the results generated by the automated analyzer and identification of abnormal or immature cells amongst other functions. This study was un...
Molecular Detection of Hepatitis C Virus (HCV) by Conventional One-step RT-PCR Coupled with Nested PCR
Aims: HCV causes both acute and chronic infections and can be easily transmitted through contaminated blood or other body fluids. The present study deals with the molecular detection of HCV with help of one-step RT-PCR a...
Thrombin Structural and Functional Determinants as Therapeutic Targets
Thrombin is the final serine protease generated during blood coagulation. This enzyme possesses a complex and fascinating structure composed not only by an active site but also by two positively charged patches, called a...
Appropriateness of Use of Blood Products in Tertiary Hospitals
Aims: This study aimed at evaluating the appropriateness of use of blood products in Northern Philippines and sought to find out if significant differences exist on the appropriateness of use of the blood products among...