Study of Biochemical Bone Bio Markers in Postmenopausal Women in PMCH Dhanbad, Jharkhand
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 6
Abstract
Aim of this study is to estimate the Serum Alkaline Phosphatase (ALP), Total Calcium, Urinary hydroxyproline and to evaluate the correlation of Age, Body Mass Index (BMI), in postmenopausal women and premenopausal women on these parameters. Serum calcium, BMI, alkaline phosphatase activities were determined in 50 premenopausal and 50 postmenopausal women in PMCH Dhanbad, Jharkhand. The mean Age, BMI, serum total ALP were significantly increased higherand calcium levels were significantly lowerin postmenopausal women when compared to premenopausal women. Bone resorption marker, urinary hydroxyproline was significantly increased in cases. This study concluded that, Serum total ALP, total calcium and Urinary hydroxyproline combined togetherprovided fairly useful index of bone resorption in postmenopausal women. Preventivemeasures like calcium supplementation or Hormone replacement therapy can be initiated early in those who are rapid bone losers and prevent the osteoporotic fractures.
Authors and Affiliations
Dr. Sunil Kumar Verma, Dr. Pramod Kumar, Dr. Neelam Agarwal
Keywords
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- EP ID EP375742
- DOI 10.9790/0853-1706030103.
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