Study of Blood Hematocrit and Platelet Aggregation in RVO.
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2017, Vol 2, Issue 6
Abstract
Retinal vein occlusion (RVO) is the second commonest cause of reduced vision due to retinal vascular disease after diabetic retinopathy. Multiple factors, both systemic and ocular, are apparently involved in the production of this retinal vascular accident.As venous stasis and blood hypercoagulability have been considered as the risk factors in retinal vein occlusion.So a case control study was undertaken to determine the levels of blood hematocrit and platelet aggregation in retinal vein occlusion. Total 60 patients of the study were divided into group A (30 patients of fundoscopically diagnosed RVO) and Group B (30 age and sex matched controls). The levels of blood hematocrit and platelet aggregation were measured.The results obtained in these patients were compared to those of controls.Data analysis was performed using Graph Pad Instat software, Version 3.05.A significantly increase in levels of blood hematocrit (p<0.05)and platelet aggregation(p<0.05) was found in group A compared to group B . The study concluded that elevated level of blood hematocrit thereby increasing the hyperviscosity and increase in the platelet aggregation may contribute to the pathogenesis and progression of RVO. Thus interventions for RVO that reduce the platelet aggregation and hematocrit will reduce the viscosity of the blood and prevent the progression and complications of RVO.
Authors and Affiliations
Dr. Samreen Rafiqu Shaikh
Keywords
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