STUDY OF CORONARY ARTERY DISEASE IN WOMEN– THE INCIDENCE OF RISK FACTORS AND CLINICAL PROFILE
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 53
Abstract
BACKGROUND Coronary Artery Disease (CAD) is the leading cause of death among women and accounts for more number of deaths than from other non-communicable diseases. Both systolic and diastolic hypertension produce more CAD events. Lowering of BP decreases Myocardial Infarction (MI) and sudden death risk. CAD risk is slightly higher among women between 49 to 89 years of age and our study showed more CAD occurred in 41 (51.25%) patients between 46-59 years of age. This study is conducted to find out the incidence of risk factors Diabetes Mellitus, Hypertension, Dyslipidaemia, Surgical/Natural Menopause and clinical profiles of CAD in women. MATERIALS AND METHODS A total of 80 female patients with the age of 38 to 80 years with clinical background of symptoms and ECG or Echo evidence of CAD admitted in M.G.M. Govt. Hospital, Tiruchirapalli. RESULTS Our study showed ST-segment Elevation Myocardial Infarction (STEMI), 33 (41.25%) patients, is more common than Non-ST segment Elevation Myocardial Infarction (NSTEMI), 16 (20%) patients, and also more STEMI in premenopausal (71.4%) than postmenopausal (34.8%). Arrhythmias are more common in women than men. Obesity, diabetes mellitus with poor glycaemic control, increased triglyceride, decreased HDL cholesterol play a significant role for the causation of CAD among newly detected patients and premenopausal than post-menopausal patients. CONCLUSION Obesity and other components of metabolic syndrome are the most important risk factors for CAD. Typical anginal symptoms of CAD are not present in old and diabetic patients, so delayed hospitalisation results in high mortality and morbidity due to fatal arrhythmias and evolved myocardial infarction leads to severe cardiac muscle damage and congestive cardiac failure (CCF). CAD mortality rate will be decreased if modifiable risk factors are identified early and treated properly
Authors and Affiliations
Thiagarajan Chakravarthi, Sappani Kasipandian, Pasupulati Venkatasamy Krishnan
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