Study of Correlation between Stress Marker Enzymes and Other Biochemical Parameters in Alcoholic Liver Disease
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 9
Abstract
Alcohol related liver disease is a major cause of morbidity and mortality worldwide. Chronic alcohol consumption leads to hepatocellular injury, fat accumulation and liver inflammation. Progression of ALD is well characterized and is actually a spectrum of liver diseases, which ranges initially from simple steatosis, to inflammation and necrosis (steatohepatitis), to fibrosis and cirrhosis. The study was designed to determine effects of stress marker enzymes and other biochemical parameters in alcoholic liver disease patients with reference to the normal healthy individuals.175 alcoholic liver disease patients were enrolled for the study & were compared to 150 normal healthy individuals of the same age. Those fulfilling inclusion & exclusion criteria were enrolled for the study & the blood samples were analysed for lipid profile, LFT, plasma MDA and SOD.Significant higher concentrations of MDA (P<0.001), GGT (P<0.001) and lower concentration of SOD (P<0.001) & Protein (p<0.001) was demonstrated in patients with alcoholic liver disease when compared with normal healthy individuals controls. The risk of alcoholic liver disease (ALD) increases in a dose & time dependent manner with consumption of alcohol.
Authors and Affiliations
Surya Tiwari, Dr. PurnimaDey Sarkar
Keywords
Related Articles
- EP ID EP480207
- DOI -
- Views 45
- Downloads 0
Epidemiology of stress fractures among athletes involved in various sports
Stress fracture is partial or complete fractures of bone that result from the repeated application of a stress less than that required to fracture a bone in a single loading situation. Stress fractures comprise between 0...
Prevalence of Thyroid Dysfunction among Pregnant Women in a Rural Teaching Hospital in Telengana, South India
Thyroid dysfunction is one of the commonest endocrinological problems in pregnanacy and affects both maternal and fetal outcomes. There is a paucity of data available on its prevalence in Indian pregnant women. This stud...
Study of Correlation between Depressive and Somatization Scores, Sociodemographic Factors Influencing them in various Subgroups of Depression
A tendency to seek treatment for medically unexplained physical complaints is frequently associated with depression; this tendency to experience and communicate psychological distress in the form of physical symptoms has...
The Role of Sonography for Diabetic Pregnancies
Gestational diabetes develops during pregnancy (gestation). Like other types of diabetes, gestational diabetes affects cells use sugar (glucose). Gestational diabetes causes high blood sugar that can affect pregnancy and...
Patterns of recurrences in carcinoma of alveolus
Abstract: In India Khaini and tobacco consumption is very high. Health awareness would certainly decrease the advanced presentation of the oral cancers to the clinicians which would help in better control of the disease....