Study of Endometrial Histopathology in Woman with Postmenopausal
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 4
Abstract
Objective: To establish the various endometrial causes of postmenopausal bleeding, through histopathological evaluation and to correlate the clinical and histopathological finding. Study Design: Prospective observational. Place and Duration of Study: The Dept of Pathology; V.S.S Medical college and Hospital, Burla, Sambalpur, 2 years duration. Methodology: A total of 105 consecutive hysterectomy specimens, endometrial biopsies and curettage samples specimens with history of postmenopausal bleeding were included. After microscopic examination, frequencies of histological findings in different age groups were generated. Chi-square and independent sample t-tests were applied to see whether the difference was significant which was set at p < 0.05. Results: Eighty two (78.10%) specimens showed benign pathologies while 19 (18.10%) were malignant. In 4 cases (3.8%) no cause for PMB was found. Endometrial hyperplasia was seen in 23 (21.9%) cases followed by endometrial polyp in 21 (20.0%). Endometrial carcinoma was found in 18 cases (17.5%). A highly significant increase in the percentage of malignant and pre-malignant lesions was seen with increasing age group (p < 0.001). Conclusion: Although benign endometrial pathologies were more common in postmenopausal bleeding but the collective proportion of endometrial malignancies was quite significant. Therefore, PMB should be urgently evaluated for cause and early commencement of treatment.
Authors and Affiliations
Kaushal Kumar, Ananya Agrawal, Shashikant Kumar, Shobhagini Nayak, K C Agrawal
Keywords
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- EP ID EP371303
- DOI 10.9790/0853-1704121720.
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