Study of genital tuberculosis and its impact on fertility in a tertiary care centre
Journal Title: Indian Journal of Obstetrics and Gynecology Research - Year 2018, Vol 5, Issue 4
Abstract
Objective To assess ovarian reserve in infertile women with genital tuberculosis and compare with women with proven fertility by hormonal and ultrasound markers of ovarian reserveMaterials and Methods A crosssectional study was conducted at an outpatient S S Hospital BHU Varanasi India with 50 women with Gestational Tuberculosis GTB and 50 healthy controls Ovarian reserve tests were done by estimating serum levels of folliclestimulating hormone FSH luteinizing hormone LH estradiol E2 on day 3 of a natural menstrual cycle and antiMullerian hormone AMH in any day of cycle On D3 Antral Follicles Count AFC were also estimated on UltrasoundResult The median FSH was 891 5601107 mIUml LH 6 465855 mIUml and the mean E2 61301523 pgml which were significantly higher than controls FSH550 LH380 and E24153 The median AMH levels 123 ngml was significantly lower in GTB than controls AMH250 And the median AFC 604080 was significantly lower in GTB than control 110 825120Conclusion The median FSH LH and the mean E2 on day3 of cycle and AMH on any day of cycle along with AFC are good predictors of Ovarian reserve and found to be low in GTB Keywords Tuberculosis Infertility Ovarian reserve Anti mullerian hormone
Authors and Affiliations
Sangeeta Rai, Prashanta Krishna Gupta
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