Study of Hepatitis E infection in a tertiary care hospital in Western Maharashtra
Journal Title: Medpulse International Journal of Medicine - Year 2018, Vol 6, Issue 2
Abstract
Background: Hepatitis E is the most common cause of acute viral hepatitis in the adult population in India. Acute viral hepatitis E (HEV) is generally mild and self-limiting and resolves within six weeks, with no chronic sequelae. Pregnant women are at increased risk with the risk increasing as the pregnancy progresses near term. Methods: Prospective study is done in Krishna Hospital at Karad in which 70 patients are taken from January 2017-march 2018 and the data is analysed for clinical and outcome of HEV. Results: Out of 70 patients, 65 presented with jaundice which is 92%, 55 presented with nausea and vomiting which is 78%,50 patients presented with anorexia which is 72%, 44 patients presented with abdominal pain which is 62%.Hepatomegaly was present in 24 patients which is 34%, bleeding problems are presented in 22 patients which is 31%.Sleep disturbances, altered consciousness are present in 16 and 12 patients which is 22% and 17%,, hepatic coagulopathy was present in 28 that is 40%, hepatic failure was present in 12 patients which is 17% and from that 3 patients died. 10 patients are having renal failure which is 14%.Out of 12 pregnant women in this study, intra uterine death occurred in 7 females that is 58%.Out of 38 females in this study, 8 females died ( maternal mortality) which is 21%Overall mortality is 11 patients died which is 15%. Conclusion: We found that majority of cases were cured with supportive treatment while risk of mortality and morbidity was more in pregnant women.
Authors and Affiliations
Makarand Mane, Priyanka Mane, Mohit Khatri, Hardik Patel
Keywords
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