A study of correlation of thyroid dysfunction on lipid abnormalities in post menopausal women
Journal Title: Medpulse International Journal of Medicine - Year 2017, Vol 1, Issue 2
Abstract
Objective: 1) To study the effects of thyroid dysfunction on lipid profile. 2) To study the prevalence of thyroid dysfunction in postmenopausal women Methods: Type of study: Prospective Randomized case control study, Sample size: 100 Postmenopausal women who will be attending the outpatient and inpatient of Medicine department in Vinayaka Missions Medical College and Hospital, Karaikal. Inclusion Criteria: Postmenopausal women attending outpatient and inpatient of Medicine Department. Exclusion Criteria: Known cases of diabetes mellitus, Known cases of Thyroid dysfunction, Known cases of hypertension, Known cases of Chronic kidney disease, Patients on Hormone replacement therapy, Diagnosed cases of Ovarian and uterine malignancy, Patients on drugs like iodide, amiodarone, salicylates, propranolol, octreotide, phenytoin, lithium, glucocorticoid, amphetamine, aminoglutethemide, somatostatins. statistically analysed. Conclusion: It was observed that postmenopausal women with thyroid dysfunction, especially subclinical hypothyroidism, had lipid abnormalities. Lipid abnormalities seen in subclinical hypothyroidism patients are mainly in the form of significant elevation of total cholesterol and HDL. According to this study, thyroid dysfunction is directly related to total cholesterol and HDL changes (p< 0.01).Changes have also been noted with thyroid dysfunction and Non HDL Cholesterol mainly LDL and VLDL but, they were not statistically significant. Therefore, in post menopausal women with thyroid dysfunction evaluation of lipid profile should be made mandatory to avoid the risk of Coronary artery disease, Cerebrovascular accident.
Authors and Affiliations
Shigil Mathew Varghese, Arun Kumar S, Babu R, Sakthivel V, Nikil Sam Varughese
Keywords
Related Articles
- EP ID EP177786
- DOI -
- Views 135
- Downloads 0
A study of the clinical profile and factors associated with guillianbarre syndrome at a tertiary care teaching hospital
Background: Guillian–Barre syndrome (GBS), also known as Landry's paralysis1, is an immune-mediated disorder of nervous system, of acute or subacute onset characterized commonly by generalized progressive weakness of low...
Study of Hepatitis E infection in a tertiary care hospital in Western Maharashtra
Background: Hepatitis E is the most common cause of acute viral hepatitis in the adult population in India. Acute viral hepatitis E (HEV) is generally mild and self-limiting and resolves within six weeks, with no chronic...
Seroprevalence of Hepatitis B in maintenance dialysis patients and associated risk factors in tertiary care institute
Background: The prevalence of HBV in dialysis population is reported to range between 3.4% to 42%. The prevalence of HBsAg depends on various factors like duration of patient being on hemodialysis, multiple blood transfu...
Relationship between lipid profile and thyroid profile in type 2 diabetes patients
Diabetes and thyroid disorders are the most common endocrinopathies in the world, they are often associated with deranged lipid profile. The present study was cross-sectional study conducted in the tertiary care centre,...
A clinical profile and factors associated with swine flu patients at tertiary health care centre
Background: Swine flu (Swine Influenza) pandemic of 2009 was started by swine origin Influenza A virus subtype H1N1 virus strain. Pregnant individuals, children under 2 years of age, young adults, and individuals with an...