Study of Histomorphological Patterns of Abnormal Uterine Bleeding On Endometrial Biopsies in a Tertiary Care Center
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 2
Abstract
Background: Normal menstrual bleeding occurs from secretory endometrium after ovulation, for a period less than 5 days. Any bleeding not complying with this is considered as abnormal uterine bleeding. Materials and methods: This is an observational study done at a Tertiary Care Center in South Tamil Nadu, in the Department of Pathology from August 2017 to January 2019, over a period of 18months. A total of 134 specimen of endometrial biopsies received, were included in the study. Aims and objectives: This study was conducted to learn the different histomorphological pattern of endometrial biopsies in patients with abnormal uterine bleeding and to find the incidence of carcinoma endometrium in our Government Tertiary Care Center. Later to evaluate the role of histopathological examination in predicting the cause on comparison with ultrasound examination. Results and conclusion: In our study, most common patterns were proliferative phase(31%) followed by secretory phase(22%) and mixed pattern(18%). The incidence of carcinoma endometrium was 3.7% in our Government Tertiary Care Center. Ultrasound diagnosis of thickened endometrium , varied from less than 10mm in functional causes to 15-30millimeters in organic causes but it could not differentiate the definitive cause. On comparison histomorphological analysis were more accurate in diagnosis of functional causes and also differentiates organic causes like carcinoma endometrium from endometrial hyperplasia. Hence endometrial biopsies can be included in the initial evaluation of women with AUB along with ultrasound examination than using it as last modality for diagnostic and therapeutic purpose irrespective of age group.
Authors and Affiliations
Dr. S. Germin Prabha, Dr. Mohan Murugesan
Keywords
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- EP ID EP467677
- DOI 10.9790/0853-1802132024.
- Views 63
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