Study of idiopathic pulmonary fibrosis in a tertiary care centre
Journal Title: IP Indian Journal of Immunology and Respiratory Medicine - Year 2018, Vol 3, Issue 4
Abstract
Introduction Idiopathic interstitial pulmonary fibrosis is an important debilitating disease among the interstitial lung diseases frequently diagnosed with the help of HRCT among the symptomaticsMaterials and Methods We have studied a total of 48 cases of IPF over a span of two and half years Among a total of 104 ILDs attending our tertiary care centre IPF constituted 48 cases accounting for 46 IPF cases are diagnosed on the basis of clinical history and hRCT findingsResults There is a female preponderance of 141 Mean age of IPF patients in our study is 579 years Mean age in females is 6071 and 539 in malesAmong our 48 cases of radiologically diagnosed IPF forty patients had definite UIP Pattern and 8 patients have possible UIP pattern as defined by the radiologist The frequency of difinite IPF cases increased with severity of symptoms as measured by MMRC scale and the association is statistically significant More than 90 of patients expressed tiresomeness and breathlessness Cough was seen in 60 and pain chest was found in 45 of IPF patients There is a statistically significant correlation of disease severity measured by MMRC scale with decrease in DLCO BAL fluid lavage showed predominant neutrophils in 90 of IPF patients Severity of IPF measured by MMRC correlated with decrease in 6 minute walk distancepSummary and Conclusion Idiopathic interstitial pulmonary fibrosis is a debilitating disease Constitutes significant proportion of ILDs Females outnumbered males Tiresomeness and breathlessness are predominat symptoms Disease occurred at a much earlier age in males Active and passive smoking possibly contributes to the severity of IPF MMRC grade correlates significantly with DLCO 6 minute walk distance and definite UIP There is no statistically significant correlation of MMRC grade with severity of PAH and FVC values Keywords Interstitial Lung Disease ILD Idiopathic Pulmonary Fibrosis IPF MMRC Grade Desaturation Broncho alveolar lavage DLCO
Authors and Affiliations
Ramakrishna Rachakonda, Nandeeswara Reddy CV
Keywords
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- EP ID EP490624
- DOI 10.18231/2581-4222.2018.0050
- Views 94
- Downloads 0
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