Study of incidence and severity of thrombocytopenia in childhood malaria and response to antimalarial therapy in a tertiary care hospital
Journal Title: Pediatric Review: International Journal of Pediatric Research - Year 2018, Vol 5, Issue 8
Abstract
Background: Malaria is a significant cause of morbidity and mortality all over world and India contributes a significant proportion of disease. There is relative paucity of data in children regarding incidence of thrombocytopenia, its severity, clinical manifestations and response to anti-malarial treatment. Materials and methods: The study conducted in a tertiary care hospital in south Rajasthan in over a period of one year includes 168 children less than 16 years with diagnosed case of malaria. Data were collected according to the medical records observation technique. Results: We found significant association of thrombocytopenia in malaria. Majority of cases with thrombocytopenia were plasmodium vivax positive, range of platelet count was 16000/cumm to 3.2lacs/cumm. Despite severe thrombocytopenia, no child had bleeding manifestations and response to treatment was significant and platelet transfusion was given to none. Conclusion: Thrombocytopenia in a febrile child in endemic zones should alert the physician towards the possibility of malaria. Moreover even in cases of severe thrombocytopenia, one should not panic and shouldgive antimalarial and appropriate supportive therapy as bleeding manifestations are rare and response to therapy is good.
Authors and Affiliations
Gaurav Dadhich, Vivek Parasher, Rahul Khatri, Sonal Bhati
Keywords
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- EP ID EP407394
- DOI 10.17511/ijpr. 2018.8.03
- Views 131
- Downloads 0
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