Study of Incidence of Rota Virus in Children under 5 Years of Age with Acute Diarrhoea with Special Reference to Characterization of Rota Virus
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 4
Abstract
Back Ground: Diarrhoea is one of the most common causes of morbidity and mortality in children worldwide. Rotavirus disease is the single most important cause of severe gastroenteritis in children throughout the world. The present study was conducted to determine the incidence of Rotavirus in diarrheal cases of children under 5 years of age and characterize rota virus strains circulating in the community. Materials and Methods: A total of 150 children under 5 years of age suffering from acute diarrhoea and 50 controls without diarrhoea were included in the present study. Rota virus was identified from all stool samples with commercially available ELISA kit detecting group specific VP6 antigen for rota virus. ELISA positive samples were subjected for characterization by RNA extraction and Reverse transcriptase Polymerase Chain Reaction. Results: Rota virus was seen significantly in children with diarrhoea. Rota virus incidence was found to be 16% among children under five years of age with diarrhoea. The genotype combination of rota virus identified were common type G1P[8],G2P[4] and uncommon type G10P[untypeable]. Conclusion: Continuous and prospective monitoring of circulating strains is necessary to detect any change in the distribution of rotavirus strains which would influence the vaccine based preventive strategies in India
Authors and Affiliations
Subha. K
Keywords
Related Articles
- EP ID EP285135
- DOI -
- Views 75
- Downloads 0
LATE- ONSET BILATERAL AUDITORY NEUROPATHY SPECTRUM DISORDER: A CASE STUDY
Background: Onset of auditory neuropathy spectrum disorder in early adulthood or middle age is exceptionally unusual. This report describes such an unusual finding of young adult onset, bilateral Auditory Neuropathy Spec...
Choice of Eye Care Giver in A Rural Community of Ebonyi State Nigeria
Background: The Federal Teaching Hospital Abakaliki Nigeria was formulating a primary eye care plan for Igbeagu Development Centre as part of the comprehensive primary health care plan for the development centre. Objecti...
Knowledge of Gestational Hypertension and Its Self Care Measures among Primigravid Women
Background: Hypertensive disorders in pregnancy is one of the major causes of maternal and perinatal morbidity and mortality. Though it cannnot the prevented, the adverse outcome can be prevented by early detection, prop...
Intravenous Haloperidol Induced Atrial Fibrillation: A Case Report
Antipsychotic drugs are known to cause adverse cardiovascular effects such as postural hypertension, tachycardia and arrhythmias. Haloperidol is one of the antipsychotic drugs and is having adverse cardiovascular effects...
Histopathological Analysis of Liver Lesions in 80 Liver Biopsy Specimens
Background: Liver biopsy serves an important role in the definitive diagnosis of liver diseases, determining the grade and stage of the disease and also in evaluating the effect of therapy. It is particularly useful in t...