Study of Iron Status in type 2 Diabetes mellitus
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 5
Abstract
Abstract: Type 2 diabetes mellitus is a clinical condition characterized by hyperglycemia due to the absolute or relative deficiency of insulin. It is also followed by pathological abnormalities like impaired insulin secretion, peripheral insulin resistance, and excessive hepatic glucose production. The objective is to study the levels of Serum Ferritin, Total Iron Binding Capacity, Iron and Hemoglobin in Type 2 Diabetes patients. A total of 120 subjects were included in this study (60 with type 2 Diabetes Mellitus, and 60 normal subjects). Fasting plasma glucose tests were done on blood samples collected after overnight fasting and 2-hour post-prandial plasma glucose was also done along with iron, total iron binding capacity (TIBC), Ferritin and hemoglobin. The level of serum Ferritin which is considered a sensitive marker of iron status was significantly higher in diabetic group. The other parameters like Hemoglobin, TIBC and Iron do not show any positive correlation. We can conclude that Serum Ferritin can be considered as sensitive marker of iron status in Diabetic group. Serum Ferritin can be assessed in non-Diabetic first-degree relatives of diabetic people for identifying the risk. Keywords:Serum Ferritin, TIBC, Serum iron, type 2 Diabetes Mellitus Fasting and Post Prandial plasma glucose
Authors and Affiliations
R J Chhabra, Neeta Kapai, Ketan Mangukiya
Keywords
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