Study of Lipid Profile in Non Diabetic Stroke in Young
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2015, Vol 3, Issue 3
Abstract
Stroke is an abrupt onset of a neurological deficit that is attributable to a focal vascular cause. It is encountered quite frequently in clinical practice. The role of circulating lipids and lipoproteins in the pathogenesis of young stroke remains uncertain even after decades of research. Diabetes is an important cause for dyslipidaemia. In this present study an attempt is made to evaluate the association between serum lipids and young non diabetic stroke patients. This study was conducted on 30 patients of young nondiabetic stroke patients. Our study included 25 patients of Ischemic stroke, 5 patients of Hemorrhagic stroke and 30 age and sex matched healthy controls. Duration of study was from September 2010 to October 2013. Patients with cerebrovascular diseases associated with diabetes, head injury, pregnancy, puerperium, infections, hepatic encephalopathy, uraemic encephalopathy, nephrotic syndrome and patients on lipid lowering drugs were excluded. Venous blood was collected for the estimation of serum total cholesterol, triglycerides, LDL-C, HDL-C, VLDL-C by standard methods. Most common age group in our study was 37-45 years comprising 53.33% of cases. Males (76.7%) were more than females (23.3%) 63.41% of patients had elevated total cholesterol (mean 210.33 + 71.61). 70% had elevated triglycerides (mean 184.93 + 74.49), High LDL-C value (mean 131.78 + 61.49) was seen in 46.7% of cases. The HDL-C levels (mean 44.71 + 17.43) was seen in 43.3% of cases, High VLDL-C value (mean 33.94+ 15.18) was seen in 56.7% of cases. The levels of total cholesterol, Triglycerides, LDL-C, TC/HDL-C, LDL-C/ HDL-C in cases were significantly raised when compared to control group (p<0.001). The levels of VLDL-C was significantly raised when compared to controls (p<0.004). The levels of HDL-C was not significantly decreased in cases when compared to control group (p<0.853). Dyslipidaemia was seen in 70% of cases. Dyslipidaemia was the first major risk factor followed by smoking (26.7%) and hypertension (23.3%). Among stroke patients smokers had significantly lower HDL-C (mean 41.23 + 15.27) and higher TC/HDL-C (mean 6.05 + 4.34) levels when compared to non smokers. Alcoholics had significantly higher HDL-C (mean 46.87 + 0.19) & lower TC/HDL-C (mean 5.01 + 3.87) levels than non alcoholics (P<0.01).Total cholesterol, Triglycerides, LDL-C, VLDL-C, TC/HDL-C, LDL-C/HDL-C were significantly raised in young stroke patients when compared to controls and had a positive correlation with the risk of stroke. Dyslipidaemia is one of the major risk factor in young non diabetic stroke patients. Thus early identification of dyslipidaemia and treatment can reduce the risk of stroke in young adults. Keywords: Non Diabetic Stroke, Lipid Profile, Young adults.
Authors and Affiliations
Nirmala A C, Mamatha TN, Priya Shree R, Avinash B H
Keywords
Related Articles
- EP ID EP373338
- DOI -
- Views 75
- Downloads 0
Comparison of diurnal intraocular pressure control between patients treated with latanoprost & surgically in primary open angle glaucoma
Abstract: The aim of this study is to compare the diurnal IOP fluctuations of Primary open angle glaucoma (POAG) patients treated with latanoprost 0.005% once a day with patients having controlled IOP after trabeculectom...
Management and Outcome Study of Snake Bite Cases in Central India
Snake-bite is a life-threatening medical emergency & major public health problem throughout the World, especially in tropical countries like India. The annual death rate due to snake bite in India is estimated to be 4.1...
Bacteriological Profile and Antibiotic Susceptibility of Pyodermas at a Tribal Tertiary Care Hospital
Abstract: Pyodermas are one of the commonest clinical conditions encountered in dermatological practice. Its prevalence, causative organism and sensitivity pattern differ from place to place.This study is conducted with...
Correlation of Classroom Attendance with Exam Performance in Ist MBBS Students In South Maharashtra
Abstract: A number of studies have shown the impact of attending the classes during the session on examination results of students. Students with good lecture attendance show good results while those with poor lecture at...
The presence of Lymphocytes in the FNAC of thyroid swelling: Straight forward case of lymphocytic thyroiditis or diagnostic dilemma
The aim of the study is to assess the presence of lymphocytes in nodular goitre and its diagnostic dilemma in FNAC. Materials and methods: Total 60 thyroid biopsy cases have been examined. Results and discussion: Out of...