Comparison of diurnal intraocular pressure control between patients treated with latanoprost & surgically in primary open angle glaucoma
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2016, Vol 4, Issue 11
Abstract
Abstract: The aim of this study is to compare the diurnal IOP fluctuations of Primary open angle glaucoma (POAG) patients treated with latanoprost 0.005% once a day with patients having controlled IOP after trabeculectomy.A total40 POAG patients were prospectively studied. The medical group consisted of 20 patients with controlled IOP (<18 mm Hg) under latanoprost 0.005% monotherapy with no history of previous intraocular surgery or laser therapy. The surgical group included 20 patients with controlled IOP after trabeculectomy without any hypotensive agent. All patients were underwent a diurnal tension curve (8:00-17:00/three hour interval), followed by a water drinking test (WDT) with last IOP measurement taken at 21:00 hours.Base line IOP (IOP at 8:00 am) was significantly lower in trabeculectomy group (10.8 mmHg) than latanoprost group (15.5 mmHg). The mean IOP during diurnal tension curve was higher in latanoprost group (15.8mm Hg) than trabeculectomy group (11.0 mmHg). After WDT, elevation of IOP was significantly higher in latanoprost than trabeculectomy group.Trabeculectomy patients had a significant lower mean IOP in diurnal tension curve than latanoprost group. Elevation of IOP in WDT and fluctuation is also lower in case of trabeculectomised patients than latanoprost group. Keywords:diurnal IOP fluctuations, Primary open angle glaucoma (POAG)
Authors and Affiliations
Debajyoti Nanda, Manisha sarkar, A K Chandrakar, M L Garg, N Pandey, Eesh Nigam
Keywords
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