Study of liver dysfunction in type 2 diabetic patients in private hospital in Cuddalore district
Journal Title: International Archives of Integrated Medicine - Year 2017, Vol 4, Issue 8
Abstract
Introduction: Diabetes is a syndrome characterized by disordered metabolism, hyperglycaemia, resulting from low levels of insulin production by beta cells of pancreas. The liver plays a major role in the regulation of carbohydrate metabolism, as it uses glucose as a fuel, it has the capability to store glucose as glycogen and also synthesize glucose from non-carbohydrate source. This key function of liver makes it vulnerable to diseases in subjects with metabolic disorders, particularly diabetes. Aim and objectives: The aim of this study was to find out the liver function test abnormalities in a group of diabetic patients and to determine the factors associated with these biochemical changes. Materials and methods: A total of 30 patients of both sexes suffering from T2DM and 30 age and sex matched normal individuals were selected for the study. The patients with fasting plasma glucose ≥126 mg/dl on 2 occasions were included in the study. Patients with any concomitant diseases which can alter liver function and patient with hepatitis, alcoholic were excluded from the study. Basic Liver Function Parameters Are Estimated Using Standard Methods. Results: The results of the present showed that the ALT, AST,PT and GGT levels in Type 2 Diabetic patients was increased significantly (p<0.01) as compared to normal controls. Conclusion: In conclusion, abnormal liver function results are more common among diabetes patients. Elevated liver enzyme markers are the markers for associated non-alcoholic fatty liver disease in diabetes patients. Testing for ALT and AST, should be carried out to screen underlying fatty liver, especially in male diabetes patients with high BMI.
Authors and Affiliations
A. Valarmathi, Lalbahadur Sastri
Keywords
Related Articles
- EP ID EP409096
- DOI -
- Views 130
- Downloads 0
The relationship between mechanical low back pain and lumbar curvature angle among computer users
Aim: To determine the relationship between mechanical low back pain and lumber curvature angle among bank worker computer users. Material and methods: 30 male bank worker computer users were working for continuous 4-hou...
Prevalence of Norovirus and epidemiology of acute gastroenteritis in children
Pediatric gastroenteritis is a major cause of childhood mortality and morbidity worldwide, especially in developing countries. Diarrhoea can be caused by a variety of different pathogens including bacteria, viruses and p...
Respiratory effects of air pollutants among non-smoking traffic policemen: An analytical cross sectional study
Background: Automobile exhaust related air pollution have become a major health hazard. Traffic police personnel, due to their continuous and prolonged exposure are likely to be the worst affected group in this regard. M...
Comparative study on hypocalcemia and maternal serum calcium level in tertiary care hospital in Chennai
Background: Hypocalcemia occurs as a manifestation of nutritional deficiency of calcium and vitamin D. Deficiency of calcium in the diet has been identified as a leading cause of nutritional rickets. Infants less than 6...
Detection of ESBL Producing Escherichia coli isolates from blood cultures and its effect on outcome of Sepsis Patients at a rural based tertiary care and teaching hospital in Vadodara district, Gujarat
Background: Sepsis is one of the most common clinical conditions that cause substantial morbidity and mortality all over the world. Blood culture is considered to be the gold standard for the identification of bacteria a...