Study of Non Diabetic Kidney Disease in Type2 Diabetic Patients with Renal Involvement
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 6
Abstract
Diabetic nephropathy (DN) is one of the major complications of Diabetes Mellitus. It is estimated that 20-40% of diabetic patients will develop a diabetic renal disease. Diabetic nephropathy is the leading cause of end stage renal disease in India and across the world. But it is not the sole renal disease in diabetic patients. Kidney diseases other than diabetic nephropathy can occur in diabetic patients, and are known as non diabetic renal disease (NDRD), either isolated or superimposed on DN. The prevalence of NDRD is very high in type 2 diabetic patients and it varies widely depending on the populations being studied and the selection criteria. Several predictive factors which can be used as pointers to NDRD have been identified by different studies. Objective: To study the prevalence, clinical spectrum and predictive factors of NDRD in type 2 diabetic patients with renal involvement. Methodology: 684 type 2 diabetic patients with renal involvement were screened, of which 646 had overt nephropathy.38 with atypical clinical renal disease were selected for the study, of which 20 had undergone renal biopsy. Patients were grouped into 3,group I-isolated NDRD, group II-isolated DN and groupIII-NDRD superimposed on DN,and their clinical and biochemical parameters were analysed. Observations and conclusions: 70% of the patients who underwent renal biopsy had NDRD with or without concurrent DN.Patients with isolated NDRD had shorter duration of diabetes compared to the other groups. Absence of retinopathy and the presence of microscopic hematuria had significant association with NDRD.IgA nephropathy was the commonest etiology of NDRD in our study.
Authors and Affiliations
Dr Gomathy S, Dr Usha Samuel, Dr Deepa K H, Dr Suma T K
Keywords
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- EP ID EP600720
- DOI 10.9790/0853-1606034350.
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