Study of prevalence of haemoglobin disorders in sindhi community with reference to HPLC
Journal Title: IP Journal of Diagnostic Pathology and Oncology - Year 2018, Vol 3, Issue 2
Abstract
Introduction Inherited haemoglobin disorders are major health problems in certain communities in different geographical areas in India These disorders pose a huge burden on affected families physically financially amp psychologically This study is carried out to find the Prevalence of these disorders in Sindhi community in Aurangabad city in state of Maharashtra IndiaMaterials and Methods The present crosssectional study was undertaken among 338 apparently healthy Sindhi individuals from community in Aurangabad Maharashtra from July 2014 to March 2017 All the samples were tested in automated hematology cell counter and then for HPLC on BioRad variant classic Various CBC parameters and Hemoglobin patterns were derived on all samplesResult The overall prevalence of Hemoglobinopathy was 60338 1775 comprised of 42 1242 cases of BTT 3 088 cases of BTM 3 088 cases of SCT 11 325 cases of Hb QIndia amp One 029 case of Hb QIndiaBTTConclusion Out of 338 samples BTT and Hb QIndia were found to be more common Hb disorders in Sindhi community Screening of community and counselling regarding the nature of these disorders are very important measures to reduce the burden of diseaseKeywords Hemoglobin disorders Prevalence HPLC betathalassemia trait Hb QIndia Maharashtra India
Authors and Affiliations
Rajan S. Bindu, Ashok K. Methwani, Anuradha R. Bindu, Preetinanda M. Dash
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