STUDY OF RESISTIVE INDEX IN VARIOUS STAGES OF LIVER CIRRHOSIS AND ITS SIGNIFICANCE IN CALCULATING THE RISK FOR HEPATORENAL SYNDROME
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2014, Vol 3, Issue 5
Abstract
[b]AIM: [/b]To evaluate resistive index in various stages of liver cirrhosis and to determine its significance in developing hepatorenal syndrome. [b]METHODS:[/b] Study included 60 cirrhotic patients divided into 4 groups (15 patients each): compensated liver cirrhosis (group A), diuretic responsive ascites (group B), refractory ascites (group C), hepatorenal syndrome (group D) and ten healthy persons as control group (E). All patients subjected to detailed history taking and clinical examination. Laboratory investigations included simple urine analysis, complete blood picture, liver function tests, blood urea and serum creatinine, serum sodium and serum potassium, and protein concentration. Ultrasonographic examination and renal duplex Doppler were under taken to assess the Resistive index. [b]RESULTS: [/b]The RI of interlobar and arcuate arteries were significantly higher in all patient groups than in control group (p <0.05), the RI was significantly higher in patients with refractory ascites than in patients with diuretic responsive ascites, and also in patient of diuretic responsible ascites than in patients with compensated cirrhosis (p < 0.05), in patient with hepatorenal syndrome than in patient with diuretic responsive ascites and patients with compensated cirrhosis (p<0.05). Also Creatinine levels & blood urea levels in patients with the hepatorenal syndrome was significantly higher than that of other different groups (p<0.05) but there was no significant change in creatinine levels between patients with compensated cirrhosis and control group. While creatinine levels in patient with diuretic responsive ascites was significantly higher than that in patient with compensated cirrhosis (p<0.05) there was no significant change between patient with diuretic responsive ascites and patient with refractory ascites. [b]CONCLUSION:[/b] Resistive index increases with degree of hepatic decompensation. Renal duplex ultrasound is a noninvasive, simple and easy method to study intrarenal hemodynamics in patients with liver cirrhosis may predict patients at risk of hepatorenal impairment.
Authors and Affiliations
Sikarwar J. S, Shilpi Muchhoria, Rashmi Singh, Harish Bhujade, Vrashbhan Ahirwar
Keywords
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- EP ID EP117305
- DOI 10.14260/jemds/2014/1968
- Views 52
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