Study of serological prevalence of transfusion transmissible infections among blood donors in a tertiary care hospital in North India
Journal Title: Indian Journal of Pathology and Oncology - Year 2018, Vol 5, Issue 2
Abstract
Introduction Blood transfusion has been subjected to risk of transfusion transmissible infections such as HIV Human Immunodeficiency Virus HBV Hepatitis B virus HCV Hepatitis C virus syphilis etc This risk has been reduced dramatically by routine screening of blood donors in blood banksObjective Our aim was to study the serological prevalence of transfusion transmissible infections TTI among donors and to find any correlation between these infections and blood groupsMethodology This is a retrospective observational study for a period of one year Dec 2014 Nov2015 and this study has been carried out in blood bank of tertiary care hospital of North India Data of all voluntary and replacement donors retrieved from blood bank records ie ABO group Rh type and results of serological tests performedResults Total 27689 donors were screened during the study period and 559 donors were found seropositive for transfusion transmissible infections 201 In which maximum 403 donors were positive for HBV 145 followed by 93HCV 033 42syphilis 015 19HIV 0068 and 2 for malaria antigen 0007 Seropositive cases for HBV HCV and MP antigen were maximum in blood group B positiveB donors While seropositive cases for syphilis were more encountered in A positive blood groupA HIV prevalence seen more in O positive groupOConclusion In this study serological prevalence among apparently healthy donors was 201 Which varies from 076 to 3 in different blood group donors So strict screening is essential for all donors to prevent these lifethreatening TTI We observed no association between blood group antigens and these transfusion transmissible infections So more studies in larger level are required to find out any associationKeywords Blood donors Transfusion transmissible infections HBV HCV HIV Blood group
Authors and Affiliations
Anita Omhare, Neetu Purwar, Sanjeev K Singh, Ujma Rana
Keywords
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- EP ID EP475489
- DOI 10.18231/2394-6792.2018.0040
- Views 67
- Downloads 0
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