Study of Serum 25-Hydroxy Vitamin D Levels in Anemia – A Case Control Study
Journal Title: International Journal of Contemporary Medical Research - Year 2016, Vol 3, Issue 3
Abstract
Introduction: Vitamin D is a fat-soluble vitamin. It has diverse biological effects extending beyond the maintenance of calcium and phosphorus homeostasis and ensuring the proper functioning of the body. Anemia and Vitamin D deficiency are both important health issues, however, the nature of association between them remain unresolved. The objectives of this study were (1) To estimate and compare the serum levels of Vitamin D in cases of anemia and healthy controls (2) To comprehend the association between Vitamin D levels and anemia. Materials and methods: It was a case control study. Thirty (n=30) diagnosed cases of anemia (hemoglobin <11g/dl) and thirty (n=30) age and sex matched healthy controls were included in the study. 25-Hydroxy vitamin D(25-OH Vitamin D) levels were measured in venous blood by chemiluminescence immunoassay method. Other hematological parameters were also measured simultaneously. Statistical analysis was done using student 't' test. Pearson's correlation was performed to establish the relationship between study variables. Results: The study showed statistically significant decrease (p<0.05) in serum 25 OH vitamin D levels in cases compared to controls. Our study showed a positive correlation between 25 OH vitamin D and hemoglobin levels. Conclusion: Anemia is associated with decreased vitamin D levels. Early detection of vitamin D deficiency and supplementation may lead to improvement of anemia.
Authors and Affiliations
Arati Ganiger, K Mallikarjuna Swamy, Shankar Prasad DS, Sangamesh V Kashinakunti
Keywords
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