Study of Serum Calcium, Microalbuminuria, Urinary Calcium/Creatinine Ratio in Postmenopausal Women
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 3
Abstract
Deficiency of estrogen increases generation and deposition of extracellular protein which causes glomerular injury. Microalbuminuria is a reflection of vascular damage and marker of early arterial disease in normal healthy individuals without diabetes and hypertension. Calcium/creatinine ratio is a well defined marker indicating the rate of bone resorption and duration of menopause. Aim of the study is to find out the presence of microalbuminuria and estimation of serum calcium and calcium/creatinine ratio are compared to that of controls. The study was conducted by taking 50 no of cases and 50 no controls. Cases include non diabetes and non hypertensive post menopausal women of 45 to 60 yr age group without taking vit D, calcium and hormone replacement therapy. Controls were of normal premenopausal women of 35 to 45 yr age group. The study showed that urinary microalbumin and urinary calcium/ creatinine ratio was significantly increasd in cases as compared to that of controls showing p<0.05. serum calcium level was significantly decreased(p<0.005) in cases which are found to be stastistically significant. Serum calcium level showed a negetive correlation with age and serum creatinine showed a negative correlation with urinary creatinine The study shows that microalbuminuria is an early indicator of subclinical organ damage. Serum calcium and ca/cr ratio can be used an early marker of bone resorption in postmenopausal women. So the above parameters can be used as screening method for detection of high risk groups who are prone to further cardiovascular disease and osteoporosis. So that early intervention can be done.
Authors and Affiliations
Dr Rita Rani Sahu
Raised serum CEA and CA 19-9 in Lung Cancer in tertiary care hospital in Eastern India
Background: Lung cancer is the leading cause of cancer death worldwide. Unfortunately, most lung cancers are already unresectable and metastatic at initial diagnosis. Measurement of tumor markers is a noninvasive means t...
Designing a Cast Partial Denture for Patients with Open Bite
Designing a cast partial denture for a partial edentulous situation often poses challenges, especially the placement of components with respect to the existing dynamic occlusion of the patient. Whereas there are many rep...
Study of Highly Sensitive C - Reactive Protein (hs-CRP) In Type 2 Diabetes Mellitus and Its Correlation with Glycosylated Hemoglobin
Background: Diabetes mellitus is one of the leading causes of morbidity and mortality. Studies have shown that hs-CRP is associated with insulin resistance, type 2 diabetes and higher HbA1c levels. This study was done to...
Comparison of Quality of Life, Depression and Self-Esteem in Patients of Vitiligo and Melasma
Background: Skin is an important interface of a human being with the world. Pigmentary disorders have psychological impact as well as impact on well-being and body image. The quality of life is affected adversely in both...
The Trends of Progesterone Hormone in Advancing Pregnancy of Human Immunodeficiency Virus-infected Women: A Cohort Study in Western Kenya
Despite many studies on Human Immunodeficiency Virus (HIV) and pregnancy, there is still insufficient information regarding the effect of HIV on progesterone in advancing pregnancy. In a prospective cohort study, 44 anti...