Study of Serum Uric Acid and C-Reactive Protein In Metabolic Syndrome Subjects With And Without Diabetes
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 17, Issue 2
Abstract
Objectives: Uric acid and highly sensitive C reactive protein (hs-CRP) are risk factors associated with the metabolic syndrome. The objective of study is to assess the level of uric acid and CRP in metabolic syndrome subjects and to compare the levels in metabolic syndrome subjects with and without diabetes mellitus Materials and methods: Detailed history and clinical examination, routine investigations and the following investigations Serum triglycerides, HDL, LDL, FBS, Serum uric acid, hs-CRP test were collected Results: Those with higher Uric acid levels had significantly higher systolic blood pressure (p=0.027) and FBS (P=0.033) than those with lower uric acid levels. 76% of patients had hs-CRP > 3 mg/l and none of the patients had hs-CRP <l mg/l. Among diabetics, 64% had higher hs-CRP level (>3mg/l) while in non diabetics 88% had hs-CRP >3 mg/l and high hs-CRP level are significantly more associated with non-diabetic (p==0.005) than diabetic. In those with uric acid >6 mg/dl, 78.4% had hs-CRP >3mg/l. Conclusion: Treating higher Uric acid and hs-CRP can decrease the progression of metabolic syndrome. Better and more strict life style changes and interventions can be implemented in those with higher uric acid and hs-CRP levels so that we can prevent complications of metabolic syndrome, specifically cardiovascular complications
Authors and Affiliations
Dr Aswini Kumar Sahoo, Dr Prahallad Chandra Mishra2, Dr Bh V K Praveen Varma3 ,, Dola Jaswanth Kumar4 ,, Dr Kamal Lochan Behera5
Keywords
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- EP ID EP364968
- DOI 10.9790/0853-1702137981
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