Study of Serum Uric Acid, C-Reactive Protein and Atherogenic Index in Coronary Artery Disease
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 1
Abstract
Coronary Artery Disease (CAD) or Ischemic Heart Disease (IHD) is the leading cause of death worldwide. Coronary artery disease has a number of well determined risk factors which include smoking, family history, hypertension, obesity, Diabetes, lack of exercise, stress and blood lipids. While the prevalence and mortality due to CHD is declining in the developed nations, there has been an alarming increase over the past two decades in the prevalence of CHD and cardiovascular mortality in India and other south Asian countries. A few studies have shown that serum uric acid has a role in the development of cardiovascular morbidity. The aim of the present study was to evaluate the level of serum uric acid, serum C - reactive protein and atherogenic index in patients with coronary artery disease. This study was conducted by taking 41 cases of coronary artery disease and 35 number of age and sex matched healthy controls. Results showed increased level of serum uric acid and atherogenic index (P<0.005) and decreased value of serum HDL- cholesterol (P<0.005) which were statistically significant. Also, we found a strong positive correlation between the atherogenic index and serum uric acid. There were many positive result for elevated C-reactive Protein. Thus, serum uric acid, atherogenic index and CRP can be helpful for risk assessment and can be used as prognostic markers for patients with ischemic heart disease.
Authors and Affiliations
Dr Suresh Kumar Sabar
Keywords
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