Study of the Frequency of Carcinoma in Solitary Thyroid Nodules and in Multinodular Goiters in Raipur C.g.india
Journal Title: IJSR-International Journal Of Scientific Research - Year 2016, Vol 5, Issue 11
Abstract
A retrospective study of all patients with goitre seen from 2011 to 2015 inclusive at the RIMS (Raipur Institute of Medical Sciences) Raipur , C.G. was made to determine the frequency of malignancy in patients with solitary non-toxic thyroid nodule (STN) and in those with multinodular goitre (MNG). There were 60 cases of STN and 178 with MNG. Nodular goitre was found to be predominantly a disease of females with sex ratios of M:F;1:7 for the STN group and of M:F;1:13 in the MNG group. The final diagnosis in all cases was made by histology which found malignancy in 10% of STN and in 5% of MNG patients, a difference which was not statistically significant.Patients in the 20-29years age group with STN appeared to have an increased risk of malignancy when compared with the MNG group. No cause for this was discovered. The predominant malignancy in the STN group of patients was papillary carcinoma, while that in the MNG group was follicular carcinoma. Since the services of a trained and experienced cytologist may not always be available in developing countries, a surgeon undertaking exploration of a STN has to decide whether to do a total thyroidectomy or not on the gross findings at operation. In MNG, re-operation would be essential if the extent of surgery is considered inadequate on the basis of the histopathology result.
Authors and Affiliations
Dr. Vinod Kumar Singh, Dr. Brajendra Kumar, Dr. Animesh Choudhary
Keywords
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